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Found 3 Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 8' and Ligand = 'BDBM15993'
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM15993(2-({2-[(3-hydroxyphenyl)amino]pyrimidin-4-yl}amino...)
Affinity DataIC50:  25nMpH: 7.2 T: 2°CAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM15993(2-({2-[(3-hydroxyphenyl)amino]pyrimidin-4-yl}amino...)
Affinity DataIC50:  25nMAssay Description:Inhibition of JNK1alpha1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM15993(2-({2-[(3-hydroxyphenyl)amino]pyrimidin-4-yl}amino...)
Affinity DataIC50:  40nMAssay Description:Inhibition of JNK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed