Compile Data Set for Download or QSAR
maximum 50k data
Found 717 with Last Name = 'shafiee' and Initial = 'a'
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Yazd University

Curated by ChEMBL
LigandPNGBDBM50052204(CHEMBL3318392)
Affinity DataKi:  1.10nMAssay Description:Mixed type inhibition of electric eel AChE using acetylthiocholine iodide substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Yazd University

Curated by ChEMBL
LigandPNGBDBM8960((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...)
Affinity DataKi:  4.20nMAssay Description:Inhibition of electric eel AChE pre-incubated for 3 mins before acetylthiocholine substrate addition by Lineweaver-Burk plotMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Yazd University

Curated by ChEMBL
LigandPNGBDBM50440441(CHEMBL2425846)
Affinity DataKi:  22nMAssay Description:Mixed-type inhibition of electric eel AChE using acetylthiocholine iodide as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Yazd University

Curated by ChEMBL
LigandPNGBDBM50080392(CHEMBL3416513)
Affinity DataKi:  270nMAssay Description:Inhibition of electric eel AChE pre-incubated for 3 mins before acetylthiocholine substrate addition by Lineweaver-Burk plotMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Yazd University

Curated by ChEMBL
LigandPNGBDBM50038390(CHEMBL3352904)
Affinity DataKi:  490nMAssay Description:Inhibition of electric eel AChE by Lineweaver-Burk plotMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Yazd University

Curated by ChEMBL
LigandPNGBDBM50204859(CHEMBL3939483)
Affinity DataKi:  490nMAssay Description:Mixed type inhibition of electric eel AChE using acetylthiocholine iodide as substrate incubated for 5 mins followed by substrate addition measured f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Yazd University

Curated by ChEMBL
LigandPNGBDBM50197934(CHEMBL3889532)
Affinity DataKi:  490nMAssay Description:Mixed-type inhibition of electric eel AChE using acetylthiocholine iodide as substrate measured for 2 mins by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Yazd University

Curated by ChEMBL
LigandPNGBDBM50020730(CHEMBL1469070)
Affinity DataKi:  1.32E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine as substrate by Lineweavere-Burk plotMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Tehran University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50235322(CHEMBL4066593)
Affinity DataIC50:  0.0700nMAssay Description:Inhibition of rat cortex AchE using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Yazd University

Curated by ChEMBL
LigandPNGBDBM50402577(CHEMBL2206129)
Affinity DataIC50:  0.110nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Yazd University

Curated by ChEMBL
LigandPNGBDBM50402583(CHEMBL2206123)
Affinity DataIC50:  0.160nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Bos taurus (bovine))
Tehran University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM9009(7-(6-Chloro-1,2,3,4-tetrahydro-acridin-9-ylamino)-...)
Affinity DataIC50:  0.200nMAssay Description:Inhibitory activity was determined against bovine liver beta galactosidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Tehran University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50235323(CHEMBL4080023)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of rat cortex AchE using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Yazd University

Curated by ChEMBL
LigandPNGBDBM50443517(CHEMBL3087899)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of electric eel AChE using acetylcholine as substrate preincubated for 15 mins prior to substrate addition by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Tehran University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50235324(CHEMBL4104258)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of rat cortex AchE using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Yazd University

Curated by ChEMBL
LigandPNGBDBM50052204(CHEMBL3318392)
Affinity DataIC50:  0.440nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide substrate by Ellman method based spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Yazd University

Curated by ChEMBL
LigandPNGBDBM50402576(CHEMBL2206130)
Affinity DataIC50:  0.460nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Yazd University

Curated by ChEMBL
LigandPNGBDBM50402587(CHEMBL2206119)
Affinity DataIC50:  0.460nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Yazd University

Curated by ChEMBL
LigandPNGBDBM50402590(CHEMBL2205576)
Affinity DataIC50:  0.470nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Bos taurus (bovine))
Tehran University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM9006(6-(1,2,3,4-Tetrahydro-acridin-9-ylamino)-hexanoic ...)
Affinity DataIC50:  1nMAssay Description:Inhibition of bovine erythrocyte AchE using acetylthiocholine as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Yazd University

Curated by ChEMBL
LigandPNGBDBM50052206(CHEMBL3318391)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide substrate by Ellman method based spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Yazd University

Curated by ChEMBL
LigandPNGBDBM50052208(CHEMBL3318394)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide substrate by Ellman method based spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Tehran University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50189988(CHEMBL214101 | Rofecoxib analogue)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Tehran University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50189989(4-(4-methylphenyl)-1-[4-(5-tetrazolyl)phenyl]-3-(t...)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Yazd University

Curated by ChEMBL
LigandPNGBDBM50443513(CHEMBL3087903)
Affinity DataIC50:  2nMAssay Description:Inhibition of electric eel AChE using acetylcholine as substrate preincubated for 15 mins prior to substrate addition by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Yazd University

Curated by ChEMBL
LigandPNGBDBM50443518(CHEMBL3087898)
Affinity DataIC50:  2nMAssay Description:Inhibition of electric eel AChE using acetylcholine as substrate preincubated for 15 mins prior to substrate addition by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Tehran University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of COX2More data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Tehran University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM16047((4S)-4-[(2S)-2-[(2R,4S,5S)-5-[(2S)-2-[(2S)-2-[(4S)...)
Affinity DataIC50:  3nMAssay Description:Inhibition of BACE1 (unknown origin) expressed in baculovirus expression system using Rh-EVNLDAEFK-Quencher as substrate after 90 mins by FRET assayMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Tehran University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50:  3.70nMAssay Description:Inhibition of COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Tehran University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50189988(CHEMBL214101 | Rofecoxib analogue)
Affinity DataIC50:  3.80nMAssay Description:Inhibition of COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Yazd University

Curated by ChEMBL
LigandPNGBDBM50073207(CHEMBL3408398)
Affinity DataIC50:  4.10nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine substrate by Ellman's reagent based methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Tehran University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50189989(4-(4-methylphenyl)-1-[4-(5-tetrazolyl)phenyl]-3-(t...)
Affinity DataIC50:  4.10nMAssay Description:Inhibition of COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Yazd University

Curated by ChEMBL
LigandPNGBDBM50052210(CHEMBL3318398)
Affinity DataIC50:  4.10nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide substrate by Ellman method based spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Yazd University

Curated by ChEMBL
LigandPNGBDBM50052212(CHEMBL3318400)
Affinity DataIC50:  4.90nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide substrate by Ellman method based spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Yazd University

Curated by ChEMBL
LigandPNGBDBM50073217(CHEMBL3408242)
Affinity DataIC50:  4.90nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine substrate by Ellman's reagent based methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Yazd University

Curated by ChEMBL
LigandPNGBDBM50440441(CHEMBL2425846)
Affinity DataIC50:  5nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 10 mins prior to substrate addition by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Yazd University

Curated by ChEMBL
LigandPNGBDBM50443515(CHEMBL3087901)
Affinity DataIC50:  5nMAssay Description:Inhibition of electric eel AChE using acetylcholine as substrate preincubated for 15 mins prior to substrate addition by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Tehran University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50204847(CHEMBL3895802)
Affinity DataIC50:  5nMAssay Description:Inhibition of human recombinant BChE using butyrylthiocholine iodide as substrate incubated for 5 mins followed by substrate addition measured for 1 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Yazd University

Curated by ChEMBL
LigandPNGBDBM50052214(CHEMBL3318402)
Affinity DataIC50:  5.20nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide substrate by Ellman method based spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Yazd University

Curated by ChEMBL
LigandPNGBDBM50073208(CHEMBL3408397)
Affinity DataIC50:  5.80nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine substrate by Ellman's reagent based methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Tehran University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50204842(CHEMBL3927698)
Affinity DataIC50:  6nMAssay Description:Inhibition of human recombinant BChE using butyrylthiocholine iodide as substrate incubated for 5 mins followed by substrate addition measured for 1 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Yazd University

Curated by ChEMBL
LigandPNGBDBM50052215(CHEMBL3318403)
Affinity DataIC50:  6.60nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide substrate by Ellman method based spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Yazd University

Curated by ChEMBL
LigandPNGBDBM50073220(CHEMBL3408241)
Affinity DataIC50:  6.80nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine substrate by Ellman's reagent based methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Tehran University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50204851(CHEMBL3947445)
Affinity DataIC50:  7nMAssay Description:Inhibition of human recombinant BChE using butyrylthiocholine iodide as substrate incubated for 5 mins followed by substrate addition measured for 1 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Tehran University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50204859(CHEMBL3939483)
Affinity DataIC50:  7nMAssay Description:Inhibition of human recombinant BChE using butyrylthiocholine iodide as substrate incubated for 5 mins followed by substrate addition measured for 1 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Tehran University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50204906(CHEMBL3911514)
Affinity DataIC50:  8nMAssay Description:Inhibition of human recombinant BChE using butyrylthiocholine iodide as substrate incubated for 5 mins followed by substrate addition measured for 1 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Tehran University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50204852(CHEMBL3982934)
Affinity DataIC50:  8nMAssay Description:Inhibition of human recombinant BChE using butyrylthiocholine iodide as substrate incubated for 5 mins followed by substrate addition measured for 1 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Yazd University

Curated by ChEMBL
LigandPNGBDBM50073202(CHEMBL3408403)
Affinity DataIC50:  8.10nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine substrate by Ellman's reagent based methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Yazd University

Curated by ChEMBL
LigandPNGBDBM50073204(CHEMBL3408401)
Affinity DataIC50:  8.70nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine substrate by Ellman's reagent based methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Tehran University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM13065(5-(4-chlorophenyl)-1-(4-methoxyphenyl)-3-(trifluor...)
Affinity DataIC50:  8.90nMAssay Description:Inhibition of COX1 in human blood assessed as PGE2 level incubated for 15 mins prior to LPS-challenge measured after 24 hrs by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 717 total ) | Next | Last >>
Jump to: