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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
63
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Target
5-hydroxytryptamine receptor 3A/3B
(Rattus norvegicus)
TBA
Ligand
BDBM50000483
((BRL 43694)1-Methyl-1H-indazole-3-carboxylic acid ...)
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Affinity Data
Ki: 0.251nM
Assay Description:
Displacement of [3H]granisetron from 5-hydroxytryptamine 3 receptor of rat cortex
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Target
5-hydroxytryptamine receptor 3A/3B
(Rattus norvegicus)
TBA
Ligand
BDBM50449636
(BRL-43694 | GRANISETRON | Kytril | LY-278584 | San...)
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Affinity Data
Ki: 0.350nM
Assay Description:
Ability to displace [3H]granisetron specifically bound to 5-hydroxytryptamine 3 receptor in rat cortical membrane
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Target
5-hydroxytryptamine receptor 3A/3B
(Rattus norvegicus)
TBA
Ligand
BDBM50449636
(BRL-43694 | GRANISETRON | Kytril | LY-278584 | San...)
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Affinity Data
Ki: 0.350nM
Assay Description:
In vitro affinity for 5-hydroxytryptamine 3 (5-HT3) receptor by displacement of [3H]BRL-43694 from rat entorhinal cortex
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Target
5-hydroxytryptamine receptor 3A/3B
(Rattus norvegicus)
TBA
Ligand
BDBM50449636
(BRL-43694 | GRANISETRON | Kytril | LY-278584 | San...)
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Affinity Data
Ki: 0.5nM
Assay Description:
Binding affinity for 5-hydroxytryptamine 3 receptor was determined by measuring displacement of [3H]GR-65630 from rat brain cortices
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Target
5-hydroxytryptamine receptor 3A/3B
(Rattus norvegicus)
TBA
Ligand
BDBM50213005
(CHEMBL306606)
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Affinity Data
Ki: 0.501nM
Assay Description:
Displacement of [3H]granisetron from 5-hydroxytryptamine 3 receptor of rat cortex
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Target
5-hydroxytryptamine receptor 3A/3B
(Rattus norvegicus)
TBA
Ligand
BDBM50000483
((BRL 43694)1-Methyl-1H-indazole-3-carboxylic acid ...)
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Affinity Data
Ki: 0.589nM
Assay Description:
Potency at neuronal 5-hydroxytryptamine 3 receptor in the rabbit heart
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Target
5-hydroxytryptamine receptor 3A/3B
(Rattus norvegicus)
TBA
Ligand
BDBM50000483
((BRL 43694)1-Methyl-1H-indazole-3-carboxylic acid ...)
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Affinity Data
Ki: 0.590nM
Assay Description:
Binding affinity for central 5-hydroxytryptamine 3 receptor was determined by displacement of [3H]-ketanserin
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Target
5-hydroxytryptamine receptor 3A/3B
(Rattus norvegicus)
TBA
Ligand
BDBM50449636
(BRL-43694 | GRANISETRON | Kytril | LY-278584 | San...)
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Affinity Data
Ki: 0.600nM
Assay Description:
Compound was evaluated for its binding affinity for 5-hydroxytryptamine 3 receptor by measuring displacement [3H]GR-65630 in rat cerebral cortex
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Target
5-hydroxytryptamine receptor 3A/3B
(Rattus norvegicus)
TBA
Ligand
BDBM50000483
((BRL 43694)1-Methyl-1H-indazole-3-carboxylic acid ...)
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Affinity Data
Ki: 0.780nM
Assay Description:
Displacement of [3H]- GR-65,630 binding to 5-hydroxytryptamine 3 receptor in rat brain cortical membranes
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Target
5-hydroxytryptamine receptor 3A/3B
(Rattus norvegicus)
TBA
Ligand
BDBM50449636
(BRL-43694 | GRANISETRON | Kytril | LY-278584 | San...)
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Affinity Data
Ki: 0.790nM
Assay Description:
Binding affinity against 5-hydroxytryptamine 3 (5-HT3) receptor in rat brain cortical membranes using radioligand [3H]quipazine
Checked by Author
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Target
5-hydroxytryptamine receptor 3A/3B
(Rattus norvegicus)
TBA
Ligand
BDBM50213009
(CHEMBL80889)
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Affinity Data
Ki: 0.794nM
Assay Description:
Displacement of [3H]granisetron from 5-hydroxytryptamine 3 receptor of rat cortex
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Target
5-hydroxytryptamine receptor 3A
(Homo sapiens (Human))
University Of Bern
Curated by
ChEMBL
Ligand
BDBM50000483
((BRL 43694)1-Methyl-1H-indazole-3-carboxylic acid ...)
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Affinity Data
Ki: 1.45nM
Assay Description:
Displacement of [3H]granisetron from human 5HT3A expressed in HEK293 cells after 1 hr by scintillation counting
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Target
5-hydroxytryptamine receptor 3A
(Homo sapiens (Human))
University Of Bern
Curated by
ChEMBL
Ligand
BDBM50000483
((BRL 43694)1-Methyl-1H-indazole-3-carboxylic acid ...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.45nM
Assay Description:
Displacement of [3H]granisetron from human 5HT3A receptor expressed in HEK293 cells by scintillation counting
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Target
5-hydroxytryptamine receptor 3A/3B
(Rattus norvegicus)
TBA
Ligand
BDBM50213001
(CHEMBL312033)
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Affinity Data
Ki: 1.60nM
Assay Description:
Displacement of [3H]granisetron from 5-hydroxytryptamine 3 receptor of rat cortex
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Target
5-hydroxytryptamine receptor 3A/3B
(Rattus norvegicus)
TBA
Ligand
BDBM50000483
((BRL 43694)1-Methyl-1H-indazole-3-carboxylic acid ...)
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Affinity Data
Ki: 1.60nM
Assay Description:
pKi value for inhibition of [3H]LY-278584 binding to 5-hydroxytryptamine 3 receptor
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Target
5-hydroxytryptamine receptor 3A/3B
(Rattus norvegicus)
TBA
Ligand
BDBM50000483
((BRL 43694)1-Methyl-1H-indazole-3-carboxylic acid ...)
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Affinity Data
Ki: 1.60nM
Assay Description:
Inhibitory activity against 5-hydroxytryptamine 3 receptor in rat cortical membranes using [3H]- 1-Methyl-1H-indazole-3-carboxylic acid (8-methyl-8-a...
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Target
5-hydroxytryptamine receptor 3A/3B
(Rattus norvegicus)
TBA
Ligand
BDBM50000483
((BRL 43694)1-Methyl-1H-indazole-3-carboxylic acid ...)
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Affinity Data
Ki: 1.70nM
Assay Description:
Displacement of the 5-hydroxytryptamine 3 receptor ligand [3H]GR-65630 from rat brain cortical membranes.
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Target
5-hydroxytryptamine receptor 3A/3B
(Rattus norvegicus)
TBA
Ligand
BDBM50000483
((BRL 43694)1-Methyl-1H-indazole-3-carboxylic acid ...)
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Affinity Data
Ki: 2nM
Assay Description:
In vitro by displacement of [3H]LY-278584 from 5-hydroxytryptamine 3 receptor on rat entorhinal cortex
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Target
5-hydroxytryptamine receptor 3A/3B
(Rattus norvegicus)
TBA
Ligand
BDBM50449636
(BRL-43694 | GRANISETRON | Kytril | LY-278584 | San...)
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Affinity Data
Ki: 2.10nM
Assay Description:
Binding affinity against radioligand [3H]quipazine labeled 5-hydroxytryptamine 3 receptor sites in neuroblastoma-glioma (NG108-15) cells.
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Target
5-hydroxytryptamine receptor 3A/3B
(Rattus norvegicus)
TBA
Ligand
BDBM50000483
((BRL 43694)1-Methyl-1H-indazole-3-carboxylic acid ...)
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Affinity Data
Ki: 2.10nM
Assay Description:
Compound was evaluated for its ability to displace [3H]quipazine binding to 5-hydroxytryptamine 3 receptor sites in NG 108-15.
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Target
5-hydroxytryptamine receptor 3A/3B
(Rattus norvegicus)
TBA
Ligand
BDBM50213002
(CHEMBL80417)
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Affinity Data
Ki: 2.5nM
Assay Description:
Displacement of [3H]granisetron from 5-hydroxytryptamine 3 receptor of rat cortex
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Target
5-hydroxytryptamine receptor 3A/3B
(Rattus norvegicus)
TBA
Ligand
BDBM50213012
(CHEMBL76601)
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Affinity Data
Ki: 3.20nM
Assay Description:
Displacement of [3H]granisetron from 5-hydroxytryptamine 3 receptor of rat cortex
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Target
5-hydroxytryptamine receptor 3A/3B
(Rattus norvegicus)
TBA
Ligand
BDBM50213011
(CHEMBL307589)
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Affinity Data
Ki: 3.20nM
Assay Description:
Displacement of [3H]granisetron from 5-hydroxytryptamine 3 receptor of rat cortex
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Target
5-hydroxytryptamine receptor 3A
(Homo sapiens (Human))
University Of Bern
Curated by
ChEMBL
Ligand
BDBM50000483
((BRL 43694)1-Methyl-1H-indazole-3-carboxylic acid ...)
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Affinity Data
Ki: 3.98nM
Assay Description:
Binding affinity to 5HT3A receptor
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Target
5-hydroxytryptamine receptor 3A
(GUINEA PIG)
Czech Republic
Curated by
ChEMBL
Ligand
BDBM50000483
((BRL 43694)1-Methyl-1H-indazole-3-carboxylic acid ...)
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Affinity Data
Ki: 4nM
Assay Description:
Antagonist activity at 5-HT3 receptor in guinea-pig ileum assessed as inhibition of 5HT-induced contraction
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Target
5-hydroxytryptamine receptor 3A
(Homo sapiens (Human))
University Of Bern
Curated by
ChEMBL
Ligand
BDBM50307818
(5-Hydroxy-1-methyl-N-[(3-endo)-9-methyl-9-azabicyc...)
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Affinity Data
Ki: 7.30nM
Assay Description:
Displacement of [3H]granisetron from human 5HT3A receptor expressed in HEK293 cells by scintillation counting
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Target
5-hydroxytryptamine receptor 3A/3B
(Rattus norvegicus)
TBA
Ligand
BDBM50000483
((BRL 43694)1-Methyl-1H-indazole-3-carboxylic acid ...)
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Affinity Data
Ki: 9.10nM
Assay Description:
Binding affinity to 5-hydroxytryptamine 3 receptor of neuronal in the afferent rabbit vagus
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Target
5-hydroxytryptamine receptor 3A
(Homo sapiens (Human))
University Of Bern
Curated by
ChEMBL
Ligand
BDBM50307827
(1-Methyl-N-[(3-endo)-9-(phenylmethyl)-9-azabicyclo...)
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Affinity Data
Ki: 59.3nM
Assay Description:
Displacement of [3H]granisetron from human 5HT3A receptor expressed in HEK293 cells by scintillation counting
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Target
5-hydroxytryptamine receptor 3A
(Homo sapiens (Human))
University Of Bern
Curated by
ChEMBL
Ligand
BDBM50307821
(6-Hydroxy-1-methyl-N-[(3-endo)-9-methyl-9-azabicyc...)
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Affinity Data
Ki: 279nM
Assay Description:
Displacement of [3H]granisetron from human 5HT3A receptor expressed in HEK293 cells by scintillation counting
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Target
5-hydroxytryptamine receptor 1B
(Rattus norvegicus (Rat))
Eli Lilly
Curated by
ChEMBL
Ligand
BDBM50000483
((BRL 43694)1-Methyl-1H-indazole-3-carboxylic acid ...)
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Affinity Data
Ki: >1.00E+3nM
Assay Description:
Inhibitory activity against 5-hydroxytryptamine 1B receptor in rat cortical membranes using [3H]5-HT as a radioligand
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Target
Serotonin 2 (5-HT2) receptor
(RAT)
Eli Lilly
Curated by
ChEMBL
Ligand
BDBM50000483
((BRL 43694)1-Methyl-1H-indazole-3-carboxylic acid ...)
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Affinity Data
Ki: >1.00E+3nM
Assay Description:
Inhibitory activity against 5-hydroxytryptamine 2 receptor in rat cortical membranes using [3H]ketanserin as a radioligand
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Target
5-hydroxytryptamine receptor 1A
(Rattus norvegicus (rat))
Eli Lilly
Curated by
ChEMBL
Ligand
BDBM50000483
((BRL 43694)1-Methyl-1H-indazole-3-carboxylic acid ...)
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Affinity Data
Ki: >1.00E+3nM
Assay Description:
Inhibitory activity against 5-hydroxytryptamine 1A receptor in rat cortical membranes using [3H]8-OH-DPAT as a radioligand
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Target
5-hydroxytryptamine receptor 1D
(RAT)
Eli Lilly
Curated by
ChEMBL
Ligand
BDBM50000483
((BRL 43694)1-Methyl-1H-indazole-3-carboxylic acid ...)
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Affinity Data
Ki: >1.00E+3nM
Assay Description:
Inhibitory activity against 5-hydroxytryptamine 3 receptor in rat cortical membranes using [3H]- 1-Methyl-1H-indazole-3-carboxylic acid (8-methyl-8-a...
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Target
5-hydroxytryptamine receptor 2C
(Rattus norvegicus (Rat))
Eli Lilly
Curated by
ChEMBL
Ligand
BDBM50000483
((BRL 43694)1-Methyl-1H-indazole-3-carboxylic acid ...)
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Affinity Data
Ki: >1.00E+3nM
Assay Description:
Inhibitory activity against 5-hydroxytryptamine 1C receptor in rat cortical membranes using [3H]mesulergine as a radioligand
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Target
5-hydroxytryptamine receptor 7
(Rattus norvegicus (rat))
National Institute Of Neurological Disorders And Stroke
Curated by
PDSP K
i
Database
Ligand
BDBM84739
(CAS_109216-58-2 | LY 278584 | NSC_3970)
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Affinity Data
Ki: 1.00E+3nM
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5-hydroxytryptamine receptor 7
(Rattus norvegicus (rat))
National Institute Of Neurological Disorders And Stroke
Curated by
PDSP K
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Database
Ligand
BDBM84739
(CAS_109216-58-2 | LY 278584 | NSC_3970)
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Ki: 1.00E+3nM
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5-hydroxytryptamine receptor 7
(Rattus norvegicus (rat))
National Institute Of Neurological Disorders And Stroke
Curated by
PDSP K
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Ligand
BDBM50000483
((BRL 43694)1-Methyl-1H-indazole-3-carboxylic acid ...)
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Ki: 1.00E+3nM
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Target
5-hydroxytryptamine receptor 7
(Rattus norvegicus (rat))
National Institute Of Neurological Disorders And Stroke
Curated by
PDSP K
i
Database
Ligand
BDBM50000483
((BRL 43694)1-Methyl-1H-indazole-3-carboxylic acid ...)
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Affinity Data
Ki: 1.00E+3nM
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Target
5-hydroxytryptamine receptor 3A/3B
(Rattus norvegicus)
TBA
Ligand
BDBM50000483
((BRL 43694)1-Methyl-1H-indazole-3-carboxylic acid ...)
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Affinity Data
Ki: >1.00E+3nM
Assay Description:
Binding affinity for central 5-hydroxytryptamine 3 receptor was determined by displacement of [3H]GR-65630
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Target
5-hydroxytryptamine receptor 3A
(Homo sapiens (Human))
University Of Bern
Curated by
ChEMBL
Ligand
BDBM50307819
(5-Methoxy-1-methyl-N-[(3-endo)-9-methyl-9-azabicyc...)
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Affinity Data
Ki: 5.31E+3nM
Assay Description:
Displacement of [3H]granisetron from human 5HT3A receptor expressed in HEK293 cells by scintillation counting
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Target
Neuronal acetylcholine receptor subunit alpha-7
(Mus musculus)
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM50000483
((BRL 43694)1-Methyl-1H-indazole-3-carboxylic acid ...)
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Affinity Data
Ki: >1.00E+4nM
Assay Description:
In vitro Binding affinity towards alpha-7 nAChR was determined
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5-hydroxytryptamine receptor 3A/3B
(Rattus norvegicus)
TBA
Ligand
BDBM50000483
((BRL 43694)1-Methyl-1H-indazole-3-carboxylic acid ...)
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Affinity Data
Ki: <1.00E+4nM
Assay Description:
5-hydroxytryptamine 3 receptor antagonist activity was confirmed by its ability to antagonize 5-HT evoked tachycardia of rabbit isolated heart
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Neuronal acetylcholine receptor subunit alpha-4/beta-2
(Homo sapiens (Human))
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM50000483
((BRL 43694)1-Methyl-1H-indazole-3-carboxylic acid ...)
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Affinity Data
Ki: 3.80E+4nM
Assay Description:
In vitro Binding affinity towards Nicotinic acetylcholine receptor alpha4-beta2 was determined
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Neuronal acetylcholine receptor subunit alpha-3
(Homo sapiens (Human))
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM50000483
((BRL 43694)1-Methyl-1H-indazole-3-carboxylic acid ...)
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Affinity Data
Ki: 6.70E+4nM
Assay Description:
In vitro Binding affinity towards 5-hydroxytryptamine 3 receptor was determined
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5-hydroxytryptamine receptor 3A
(Homo sapiens (Human))
University Of Bern
Curated by
ChEMBL
Ligand
BDBM221527
(US9303045, 12 | US9695195, 12)
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Affinity Data
IC50: 0.450nM
T: 2°C
Assay Description:
The 5HT3 antagonist activity of the compounds of the invention was determined by measuring the ability of the compounds to inhibit the calcium flux a...
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Target
5-hydroxytryptamine receptor 3A
(Homo sapiens (Human))
University Of Bern
Curated by
ChEMBL
Ligand
BDBM221527
(US9303045, 12 | US9695195, 12)
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Affinity Data
IC50: 0.450nM
T: 2°C
Assay Description:
The 5HT3 antagonist activity of the compounds of the invention was determined by measuring the ability of the compounds to inhibit the calcium flux a...
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5-hydroxytryptamine receptor 4
(GUINEA PIG)
Universidad De Alcal£
Curated by
ChEMBL
Ligand
BDBM50000483
((BRL 43694)1-Methyl-1H-indazole-3-carboxylic acid ...)
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Affinity Data
IC50: >1.00E+3nM
Assay Description:
Binding affinity towards 5-HT3 receptor in rat was evaluated
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D(2) dopamine receptor
(Rattus norvegicus (rat))
Universidad De Alcal£
Curated by
ChEMBL
Ligand
BDBM50000483
((BRL 43694)1-Methyl-1H-indazole-3-carboxylic acid ...)
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Affinity Data
IC50: >1.00E+3nM
Assay Description:
Binding affinity towards 5-HT3 receptor in rat was evaluated
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5-hydroxytryptamine receptor 3A/3B
(Rattus norvegicus)
TBA
Ligand
BDBM50000483
((BRL 43694)1-Methyl-1H-indazole-3-carboxylic acid ...)
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Affinity Data
IC50: 1.76E+3nM
Assay Description:
Binding affinity towards 5-HT3 receptor in rat was evaluated
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Target
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human))
Reverse Proteomics Research Institute
Curated by
ChEMBL
Ligand
BDBM50000483
((BRL 43694)1-Methyl-1H-indazole-3-carboxylic acid ...)
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Affinity Data
IC50: 3.72E+3nM
Assay Description:
Inhibitory concentration against potassium channel HERG
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Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human))
Reverse Proteomics Research Institute
Curated by
ChEMBL
Ligand
BDBM50000483
((BRL 43694)1-Methyl-1H-indazole-3-carboxylic acid ...)
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Affinity Data
IC50: 3.73E+3nM
Assay Description:
K+ channel blocking activity in human embryonic kidney cells expressing HERG Kv11.1
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Target
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human))
Reverse Proteomics Research Institute
Curated by
ChEMBL
Ligand
BDBM50000483
((BRL 43694)1-Methyl-1H-indazole-3-carboxylic acid ...)
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Affinity Data
IC50: 3.80E+3nM
Assay Description:
Inhibition of human ERG
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Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human))
Reverse Proteomics Research Institute
Curated by
ChEMBL
Ligand
BDBM50000483
((BRL 43694)1-Methyl-1H-indazole-3-carboxylic acid ...)
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IC50: 3.80E+3nM
Assay Description:
Inhibition of human ERG in MCF7 cells
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Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human))
Reverse Proteomics Research Institute
Curated by
ChEMBL
Ligand
BDBM50449636
(BRL-43694 | GRANISETRON | Kytril | LY-278584 | San...)
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Affinity Data
IC50: 3.80E+3nM
Assay Description:
Inhibition of partially open human voltage-gated potassium channel subunit Kv11.1 (ERG K+ channel)
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Target
Solute carrier family 22 member 2
(Homo sapiens (Human))
University Of California
Curated by
ChEMBL
Ligand
BDBM50000483
((BRL 43694)1-Methyl-1H-indazole-3-carboxylic acid ...)
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Affinity Data
IC50: 4.30E+3nM
Assay Description:
Inhibition of human OCT2-mediated ASP+ uptake expressed in HEK293 cells after 3 mins by fluorescence assay
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Multidrug and toxin extrusion protein 1
(Homo sapiens (Human))
University Of California
Curated by
ChEMBL
Ligand
BDBM50000483
((BRL 43694)1-Methyl-1H-indazole-3-carboxylic acid ...)
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Affinity Data
IC50: 5.00E+3nM
Assay Description:
Inhibition of human MATE1-mediated ASP+ uptake expressed in HEK293 cells after 1.5 mins by fluorescence assay
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Multidrug and toxin extrusion protein 2
(Homo sapiens (Human))
University Of California
Curated by
ChEMBL
Ligand
BDBM50000483
((BRL 43694)1-Methyl-1H-indazole-3-carboxylic acid ...)
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Affinity Data
IC50: 3.11E+5nM
Assay Description:
Inhibition of human MATE2K-mediated ASP+ uptake expressed in HEK293 cells after 1.5 mins by fluorescence assay
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5-hydroxytryptamine receptor 3A
(Homo sapiens (Human))
University Of Bern
Curated by
ChEMBL
Ligand
BDBM50443668
(CHEBI:5537 | CHEMBL1290003 | GRANISETRON)
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Affinity Data
EC50: 320nM
Assay Description:
Agonist activity at human wild type 5-HT3A receptor expressed in HEK293 cells by FLIPR assay
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Target
5-hydroxytryptamine receptor 3A/3B
(Mus musculus (house mouse))
Merrell Dow Research Institute
Curated by
ChEMBL
Ligand
BDBM50000483
((BRL 43694)1-Methyl-1H-indazole-3-carboxylic acid ...)
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Affinity Data
Kd: 1.40nM
Assay Description:
Binding affinity towards 5-hydroxytryptamine 3 receptor was determined by using [3H]-ICS 205-930 as radioligand in mouse N1E 115 cells
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Target
5-hydroxytryptamine receptor 3A/3B
(Mus musculus (house mouse))
Merrell Dow Research Institute
Curated by
ChEMBL
Ligand
BDBM50000483
((BRL 43694)1-Methyl-1H-indazole-3-carboxylic acid ...)
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Affinity Data
Kd: 1.30nM
Assay Description:
Antagonistic activity against Serotonin 5-hydroxytryptamine 3 receptor in isolated rabbit vagus nerve (RVN)
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5-hydroxytryptamine receptor 3A/3B
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50443668
(CHEBI:5537 | CHEMBL1290003 | GRANISETRON)
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Affinity Data
Kd: 0.200nM
Assay Description:
Binding affinity to human wild type 5-HT3A/5-HT3B receptor expressed in HEK293 cells after 24 hrs by liquid scintillation counting analysis
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Target
5-hydroxytryptamine receptor 3A
(Homo sapiens (Human))
University Of Bern
Curated by
ChEMBL
Ligand
BDBM50443668
(CHEBI:5537 | CHEMBL1290003 | GRANISETRON)
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Affinity Data
Kd: 0.530nM
Assay Description:
Binding affinity to human wild type 5-HT3A receptor expressed in HEK293 cells after 24 hrs by liquid scintillation counting analysis
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Target
5-hydroxytryptamine receptor 3A/3B
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50443668
(CHEBI:5537 | CHEMBL1290003 | GRANISETRON)
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Affinity Data
EC50: 500nM
Assay Description:
Agonist activity at human wild type 5-HT3A/5-HT3B receptor expressed in HEK293 cells by FLIPR assay
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