Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 18 hits in this display
BDBM82232(CAS_8977 | GDP | NSC_8977)
BDBM82232(CAS_8977 | GDP | NSC_8977)
BDBM92459(CHEMBL384759 | GDP | Guanosine Diphosphate)
Ki: 7.79E+4nMAssay Description:Inhibition of human recombinant alpha1,3-fucosyltransferase 9 using GDP-[14C]-fucose preincubated for 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
BDBM223202(β,γ-methyleneguanosine 5′-triphosp...)
BDBM223202(β,γ-methyleneguanosine 5′-triphosp...)
Ki: 6.96E+5nMAssay Description:The inhibition of H477R PEPCK by β-sulfopyruvate (βSP), oxalate, and GMPPCP was conducted in the direction of PEP synthesis (OAA → PE...More data for this Ligand-Target Pair
BDBM50300554(((2S,3R,4S,5S)-5-(2-amino-6-oxo-1H-purin-9(6H)-yl)...)
IC50: 1.40E+3nMAssay Description:Inhibition of Cdc42 GTPase activity assessed as incorporation of BODIPY-GTP after 40 mins by nucleotide binding competition assayMore data for this Ligand-Target Pair
BDBM92459(CHEMBL384759 | GDP | Guanosine Diphosphate)
BDBM50300554(((2S,3R,4S,5S)-5-(2-amino-6-oxo-1H-purin-9(6H)-yl)...)
IC50: 2.70E+3nMAssay Description:Inhibition of Rac1 GTPase activity assessed as incorporation of BODIPY-GTP after 40 mins by nucleotide binding competition assayMore data for this Ligand-Target Pair
BDBM92459(CHEMBL384759 | GDP | Guanosine Diphosphate)
IC50: 2.40E+4nMpH: 7.3 T: 2°CAssay Description:A radioligand-binding assay was developed using scintillation proximity assay (SPA) technology. The wheat germ agglutinin SPA beads (Amersham) (0.2 m...More data for this Ligand-Target Pair
BDBM92459(CHEMBL384759 | GDP | Guanosine Diphosphate)
IC50: 5.90E+4nMAssay Description:Inhibition of human recombinant alpha1,3-fucosyltransferase 9 using GDP-[14C]-fucose preincubated for 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
BDBM92459(CHEMBL384759 | GDP | Guanosine Diphosphate)
BDBM92459(CHEMBL384759 | GDP | Guanosine Diphosphate)
BDBM92459(CHEMBL384759 | GDP | Guanosine Diphosphate)
IC50: >2.00E+5nMpH: 7.5 T: 2°CAssay Description:A radioligand-binding assay was developed using scintillation proximity assay (SPA) technology. The wheat germ agglutinin SPA beads (Amersham) (0.2 m...More data for this Ligand-Target Pair
Matrilysin(Homo sapiens (Human))Schering-Plough Research Institute
BDBM92459(CHEMBL384759 | GDP | Guanosine Diphosphate)
IC50: >2.00E+5nMpH: 7.5 T: 2°CAssay Description:A radioligand-binding assay was developed using scintillation proximity assay (SPA) technology. The wheat germ agglutinin SPA beads (Amersham) (0.2 m...More data for this Ligand-Target Pair
BDBM92459(CHEMBL384759 | GDP | Guanosine Diphosphate)
IC50: >2.00E+5nMpH: 7.3 T: 2°CAssay Description:A radioligand-binding assay was developed using scintillation proximity assay (SPA) technology. The wheat germ agglutinin SPA beads (Amersham) (0.2 m...More data for this Ligand-Target Pair
BDBM50101907(({[(2R,3S,4R,5R)-5-(2-azaniumyl-6-hydroxy-9H-purin...)
P2Y purinoceptor 6(Homo sapiens (Human))National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
BDBM92459(CHEMBL384759 | GDP | Guanosine Diphosphate)
EC50: 4.50E+4nMAssay Description:Agonist activity at human recombinant P2Y6 receptor expressed in 1321N1 cells assessed as PLC-mediated [3H]IP productionMore data for this Ligand-Target Pair
BDBM92459(CHEMBL384759 | GDP | Guanosine Diphosphate)