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Compile Data Set for Download or QSAR

Found 3 hits of ec50 data for polymerid = 9018   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
NMDA receptor subunit 2C (GluN2C)


(Rattus norvegicus (Rat))
BDBM50038162
PNG
(5,7-Dinitro-1,4-dihydro-quinoxaline-2,3-dione | CH...)
Show SMILES [O-][N+](=O)c1cc([N+]([O-])=O)c2[nH]c(=O)c(=[OH+])[n-]c2c1
Show InChI InChI=1S/C8H4N4O6/c13-7-8(14)10-6-4(9-7)1-3(11(15)16)2-5(6)12(17)18/h1-2H,(H2,9,10,13,14)
UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Patents

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PubMed
n/an/an/an/a 400n/an/an/an/a



Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Compound was evaluated for in vitro inhibition of [3H]-GABA release at NMDA receptor.


J Med Chem 37: 4053-67 (1995)

More data for this
Ligand-Target Pair
NMDA receptor subunit 2C (GluN2C)


(Rattus norvegicus (Rat))
BDBM50038178
PNG
((+)-4-Amino-3-isoxazolidinone | (4R)-4-aminoisoxaz...)
Show SMILES N[C@@H]1CON=C1O
Show InChI InChI=1S/C3H6N2O2/c4-2-1-7-5-3(2)6/h2H,1,4H2,(H,5,6)/t2-/m1/s1
UniProtKB/SwissProt

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CHEMBL
MMDB
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
PubMed
n/an/an/an/a 1.81E+4n/an/an/an/a



Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Compound was evaluated for in vitro inhibition of [3H]-TCP at NMDA receptor.


J Med Chem 37: 4053-67 (1995)

More data for this
Ligand-Target Pair
NMDA receptor subunit 2C (GluN2C)


(Rattus norvegicus (Rat))
BDBM50004938
PNG
(3-Carboxymethylsulfanyl-4,6-dichloro-1H-indole-2-c...)
Show SMILES OC(=O)CSc1c([nH]c2cc(Cl)cc(Cl)c12)C(O)=O
Show InChI InChI=1S/C11H7Cl2NO4S/c12-4-1-5(13)8-6(2-4)14-9(11(17)18)10(8)19-3-7(15)16/h1-2,14H,3H2,(H,15,16)(H,17,18)
UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

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PubMed
n/an/an/an/a 1.40E+5n/an/an/an/a



Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Compound was evaluated for in vitro inhibition of cortical slice at NMDA receptor


J Med Chem 37: 4053-67 (1995)

More data for this
Ligand-Target Pair