BDBM50038162 5,7-Dinitro-1,4-dihydro-quinoxaline-2,3-dione::CHEMBL323335

SMILES [O-][N+](=O)c1cc([N+]([O-])=O)c2[nH]c(=O)c(=[OH+])[n-]c2c1

InChI Key InChIKey=WAKDFGDQGHWALM-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50038162   

TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50038162(5,7-Dinitro-1,4-dihydro-quinoxaline-2,3-dione | CH...)
Affinity DataEC50:  400nMAssay Description:Compound was evaluated for in vitro inhibition of [3H]-GABA release at NMDA receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50038162(5,7-Dinitro-1,4-dihydro-quinoxaline-2,3-dione | CH...)
Affinity DataIC50:  400nMAssay Description:Compound was evaluated for in vitro inhibition of cortical slice release at NMDA receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50038162(5,7-Dinitro-1,4-dihydro-quinoxaline-2,3-dione | CH...)
Affinity DataIC50:  170nMAssay Description:Compound was evaluated for in vitro inhibition of [3H]L-689,560 at NMDA receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed