Found 2120 Enz. Inhib. hit(s) with Target = 'Aminopeptidase' 
Affinity DataIC50: >1.00E+5nMpH: 7.2Assay Description:Briefly, the assay was performed in 96-well plates in 50 mm PBS, pH 7.2 as the assay buffer, at 37 °C. The APN solution was mixed with compounds at v...More data for this Ligand-Target Pair
Affinity DataIC50: 6.25E+3nMpH: 7.2Assay Description:IC50 values against APN were determined as previously described and by using L-Leu-p-nitroanilide as a substrate and microsomal aminopeptidase from P...More data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataIC50: >1.00E+5nMpH: 7.2Assay Description:Briefly, the assay was performed in 96-well plates in 50 mm PBS, pH 7.2 as the assay buffer, at 37 °C. The APN solution was mixed with compounds at v...More data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+3nMpH: 7.2Assay Description:Briefly, the assay was performed in 96-well plates in 50 mm PBS, pH 7.2 as the assay buffer, at 37 °C. The APN solution was mixed with compounds at v...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMpH: 7.2Assay Description:Briefly, the assay was performed in 96-well plates in 50 mm PBS, pH 7.2 as the assay buffer, at 37 °C. The APN solution was mixed with compounds at v...More data for this Ligand-Target Pair
Affinity DataIC50: 6.50E+3nMpH: 7.2Assay Description:IC50 values against APN were determined as previously described and by using L-Leu-p-nitroanilide as a substrate and microsomal aminopeptidase from P...More data for this Ligand-Target Pair
Affinity DataIC50: 1.75E+4nMpH: 7.2Assay Description:IC50 values against APN were determined as previously described and by using L-Leu-p-nitroanilide as a substrate and microsomal aminopeptidase from P...More data for this Ligand-Target Pair
Affinity DataIC50: 2.51E+3nMpH: 7.2Assay Description:IC50 values against APN were determined as previously described and by using L-Leu-p-nitroanilide as a substrate and microsomal aminopeptidase from P...More data for this Ligand-Target Pair
Affinity DataIC50: 1.16E+4nMpH: 7.2Assay Description:IC50 values against APN were determined as previously described and by using L-Leu-p-nitroanilide as a substrate and microsomal aminopeptidase from P...More data for this Ligand-Target Pair
Affinity DataIC50: 5.16E+3nMpH: 7.2Assay Description:IC50 values against APN were determined as previously described and by using L-Leu-p-nitroanilide as a substrate and microsomal aminopeptidase from P...More data for this Ligand-Target Pair
Affinity DataIC50: 6.50E+3nMpH: 7.2Assay Description:IC50 values against APN were determined as previously described and by using L-Leu-p-nitroanilide as a substrate and microsomal aminopeptidase from P...More data for this Ligand-Target Pair
Affinity DataIC50: 5.80E+3nMpH: 7.2Assay Description:IC50 values against APN were determined as previously described and by using L-Leu-p-nitroanilide as a substrate and microsomal aminopeptidase from P...More data for this Ligand-Target Pair
Affinity DataIC50: 1.36E+4nMpH: 7.2Assay Description:IC50 values against APN were determined as previously described and by using L-Leu-p-nitroanilide as a substrate and microsomal aminopeptidase from P...More data for this Ligand-Target Pair
Affinity DataIC50: 1.15E+4nMpH: 7.2Assay Description:IC50 values against APN were determined as previously described and by using L-Leu-p-nitroanilide as a substrate and microsomal aminopeptidase from P...More data for this Ligand-Target Pair
Affinity DataIC50: 3.02E+4nMpH: 7.2Assay Description:IC50 values against APN were determined as previously described and by using L-Leu-p-nitroanilide as a substrate and microsomal aminopeptidase from P...More data for this Ligand-Target Pair
Affinity DataIC50: 5.15E+4nMpH: 7.2Assay Description:IC50 values against APN were determined as previously described and by using L-Leu-p-nitroanilide as a substrate and microsomal aminopeptidase from P...More data for this Ligand-Target Pair
Affinity DataIC50: 9.40E+4nMpH: 7.2Assay Description:IC50 values against APN were determined as previously described and by using L-Leu-p-nitroanilide as a substrate and microsomal aminopeptidase from P...More data for this Ligand-Target Pair
Affinity DataIC50: 3.04E+4nMpH: 7.2Assay Description:IC50 values against APN were determined as previously described and by using L-Leu-p-nitroanilide as a substrate and microsomal aminopeptidase from P...More data for this Ligand-Target Pair
Affinity DataIC50: 2.55E+3nMpH: 7.5 T: 2°CAssay Description:IC50 values against APN from Porcine Kidney were determined by using L-Leu-p-nitroanilide as a substrate. All the solutions of the inhibitors were pr...More data for this Ligand-Target Pair
Affinity DataIC50: 3.52E+5nMpH: 7.5 T: 2°CAssay Description:IC50 values against APN from Porcine Kidney were determined by using L-Leu-p-nitroanilide as a substrate. All the solutions of the inhibitors were pr...More data for this Ligand-Target Pair
Affinity DataIC50: 1.58E+5nMpH: 7.5 T: 2°CAssay Description:IC50 values against APN from Porcine Kidney were determined by using L-Leu-p-nitroanilide as a substrate. All the solutions of the inhibitors were pr...More data for this Ligand-Target Pair
Affinity DataIC50: 1.73E+5nMpH: 7.5 T: 2°CAssay Description:IC50 values against APN from Porcine Kidney were determined by using L-Leu-p-nitroanilide as a substrate. All the solutions of the inhibitors were pr...More data for this Ligand-Target Pair
Affinity DataIC50: 4.40E+4nMpH: 7.5 T: 2°CAssay Description:IC50 values against APN from Porcine Kidney were determined by using L-Leu-p-nitroanilide as a substrate. All the solutions of the inhibitors were pr...More data for this Ligand-Target Pair
Affinity DataIC50: 1.26E+3nMpH: 7.5 T: 2°CAssay Description:IC50 values against APN from Porcine Kidney were determined by using L-Leu-p-nitroanilide as a substrate. All the solutions of the inhibitors were pr...More data for this Ligand-Target Pair
Affinity DataIC50: 8.29E+4nMpH: 7.5 T: 2°CAssay Description:IC50 values against APN from Porcine Kidney were determined by using L-Leu-p-nitroanilide as a substrate. All the solutions of the inhibitors were pr...More data for this Ligand-Target Pair
Affinity DataIC50: 7.70E+4nMpH: 7.5 T: 2°CAssay Description:IC50 values against APN from Porcine Kidney were determined by using L-Leu-p-nitroanilide as a substrate. All the solutions of the inhibitors were pr...More data for this Ligand-Target Pair
Affinity DataIC50: 5.67E+4nMpH: 7.5 T: 2°CAssay Description:IC50 values against APN from Porcine Kidney were determined by using L-Leu-p-nitroanilide as a substrate. All the solutions of the inhibitors were pr...More data for this Ligand-Target Pair
Affinity DataIC50: 1.05E+5nMpH: 7.5 T: 2°CAssay Description:IC50 values against APN from Porcine Kidney were determined by using L-Leu-p-nitroanilide as a substrate. All the solutions of the inhibitors were pr...More data for this Ligand-Target Pair
Affinity DataIC50: 5.13E+5nMpH: 7.5 T: 2°CAssay Description:IC50 values against APN from Porcine Kidney were determined by using L-Leu-p-nitroanilide as a substrate. All the solutions of the inhibitors were pr...More data for this Ligand-Target Pair
Affinity DataIC50: 5.90E+5nMpH: 7.5 T: 2°CAssay Description:IC50 values against APN from Porcine Kidney were determined by using L-Leu-p-nitroanilide as a substrate. All the solutions of the inhibitors were pr...More data for this Ligand-Target Pair
Affinity DataIC50: 1.98E+5nMpH: 7.5 T: 2°CAssay Description:IC50 values against APN from Porcine Kidney were determined by using L-Leu-p-nitroanilide as a substrate. All the solutions of the inhibitors were pr...More data for this Ligand-Target Pair
Affinity DataIC50: 3.42E+5nMpH: 7.5 T: 2°CAssay Description:IC50 values against APN from Porcine Kidney were determined by using L-Leu-p-nitroanilide as a substrate. All the solutions of the inhibitors were pr...More data for this Ligand-Target Pair
Affinity DataIC50: 3.63E+5nMpH: 7.5 T: 2°CAssay Description:IC50 values against APN from Porcine Kidney were determined by using L-Leu-p-nitroanilide as a substrate. All the solutions of the inhibitors were pr...More data for this Ligand-Target Pair
Affinity DataKi: 0nMAssay Description:Inhibitory activity was measured on pig kidney Aminopeptidase N (activity for C+D stereoisomer)More data for this Ligand-Target Pair
Affinity DataKi: 0nMAssay Description:Inhibitory activity was measured on pig kidney Aminopeptidase N (activity for C+D stereoisomer)More data for this Ligand-Target Pair
Affinity DataKi: >0nMAssay Description:Inhibitory activity was measured on Aminopeptidase B using Arg p.NA as substrateMore data for this Ligand-Target Pair
Affinity DataKi: >0nMAssay Description:Inhibitory activity was measured on Aminopeptidase B using Arg p.NA as substrateMore data for this Ligand-Target Pair
Affinity DataKi: 0.0600nMAssay Description:Inhibition of porcine kidney APN using L-leucine-p-nitroanilide as substrate after 30 mins by Dixon plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 0.0600nMAssay Description:Inhibition of pig APN using L-leucine-p-nitroanilide as substrate measured every 10 mins for 2 hrs by spectriphotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 0.0600nMAssay Description:Inhibition of human APNMore data for this Ligand-Target Pair
Affinity DataKi: 0.160nMAssay Description:Inhibition of human recombinant alanyl aminopeptidase after 30 to 60 mins by morrison's equationMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Inhibition of mouse APN using L-leucine-p-nitroanilide as substrate measured every 10 mins for 2 hrs by spectriphotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 0.210nMAssay Description:Inhibition of human recombinant alanyl aminopeptidase after 30 to 60 mins by morrison's equationMore data for this Ligand-Target Pair
Affinity DataKi: 0.230nMAssay Description:Inhibition of human recombinant alanyl aminopeptidase after 30 to 60 mins by morrison's equationMore data for this Ligand-Target Pair
Affinity DataKi: 0.350nMAssay Description:Inhibition of human APN using L-leucine-p-nitroanilide as substrate measured every 10 mins for 2 hrs by spectriphotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Competitive inhibition of pig APN using L-leucine-p-nitroanilide as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Inhibition of APN in porcine kidney using Ala-p-NA as substrateMore data for this Ligand-Target Pair
Affinity DataKi: 0.690nMAssay Description:Inhibition of human recombinant alanyl aminopeptidase after 30 to 60 mins by morrison's equationMore data for this Ligand-Target Pair
Affinity DataKi: 0.790nMAssay Description:Inhibition of human recombinant alanyl aminopeptidase after 30 to 60 mins by morrison's equationMore data for this Ligand-Target Pair
Affinity DataKi: 0.840nMAssay Description:Inhibition of aminopeptidase B or arginyl aminopeptidase purified from rat liverMore data for this Ligand-Target Pair
