Compile Data Set for Download or QSAR
maximum 50k data
Found 35 Enz. Inhib. hit(s) with all data for entry = 50008695
TargetSerine protease 1(Bos taurus (bovine))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076227((1S,7S)-7-Amino-7-benzyl-hexahydro-pyrazolo[1,2-a]...)
Affinity DataKi:  0.0270nMAssay Description:Inhibitory concentration of the compound against trypsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076227((1S,7S)-7-Amino-7-benzyl-hexahydro-pyrazolo[1,2-a]...)
Affinity DataKi:  0.0710nMAssay Description:Inhibitory concentration of the compound against thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076224((1S,7S)-7-Amino-7-benzyl-hexahydro-pyrazolo[1,2-a]...)
Affinity DataKi:  0.0730nMAssay Description:Inhibitory concentration of the compound against thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076224((1S,7S)-7-Amino-7-benzyl-hexahydro-pyrazolo[1,2-a]...)
Affinity DataKi:  0.0730nMAssay Description:Inhibitory concentration of the compound against trypsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076219((3S,6R)-6-Amino-6-benzyl-octahydro-indolizine-3-ca...)
Affinity DataKi:  0.230nMAssay Description:Inhibitory concentration of the compound against trypsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076223((1S,7S)-7-Amino-7-benzyl-hexahydro-pyrazolo[1,2-a]...)
Affinity DataKi:  0.310nMAssay Description:Inhibitory concentration of the compound against thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076225((1S,7S)-7-Amino-7-benzyl-hexahydro-pyrazolo[1,2-a]...)
Affinity DataKi:  0.450nMAssay Description:Inhibitory concentration of the compound against thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076222((1S,7S)-7-Amino-7-benzyl-hexahydro-pyrazolo[1,2-a]...)
Affinity DataKi:  0.640nMAssay Description:Inhibitory concentration of the compound against trypsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076222((1S,7S)-7-Amino-7-benzyl-hexahydro-pyrazolo[1,2-a]...)
Affinity DataKi:  0.650nMAssay Description:Inhibitory concentration of the compound against thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076219((3S,6R)-6-Amino-6-benzyl-octahydro-indolizine-3-ca...)
Affinity DataKi:  0.850nMAssay Description:Inhibitory concentration of the compound against thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076219((3S,6R)-6-Amino-6-benzyl-octahydro-indolizine-3-ca...)
Affinity DataKi:  0.850nMAssay Description:Inhibitory concentration of the compound against thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076228((1S,7S)-7-Amino-7-benzyl-hexahydro-pyrazolo[1,2-a]...)
Affinity DataKi:  2.40nMAssay Description:Inhibitory concentration of the compound against thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076221((S)-1-((R)-2-Amino-3-phenyl-propionyl)-pyrrolidine...)
Affinity DataKi:  106nMAssay Description:Compound was evaluated for the inhibition of Tissue type plasminogen activator (tissue plasminogen activator)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076220((1S,7S)-7-Amino-7-benzyl-hexahydro-pyrazolo[1,2-a]...)
Affinity DataKi:  140nMAssay Description:Inhibitory concentration of the compound against coagulation factor VIIaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076221((S)-1-((R)-2-Amino-3-phenyl-propionyl)-pyrrolidine...)
Affinity DataKi:  165nMAssay Description:Inhibitory concentration of the compound against Coagulation factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076221((S)-1-((R)-2-Amino-3-phenyl-propionyl)-pyrrolidine...)
Affinity DataKi:  200nMAssay Description:Inhibitory concentration of the compound against coagulation factor VIIaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076220((1S,7S)-7-Amino-7-benzyl-hexahydro-pyrazolo[1,2-a]...)
Affinity DataKi:  385nMAssay Description:Inhibitory concentration of the compound against Coagulation factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076221((S)-1-((R)-2-Amino-3-phenyl-propionyl)-pyrrolidine...)
Affinity DataKi:  508nMAssay Description:Inhibitory concentration of the compound against Urokinase-type plasminogen activatorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076220((1S,7S)-7-Amino-7-benzyl-hexahydro-pyrazolo[1,2-a]...)
Affinity DataKi:  632nMAssay Description:Inhibitory concentration of the compound against Tissue type plasminogen activatorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Rattus norvegicus)
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076221((S)-1-((R)-2-Amino-3-phenyl-propionyl)-pyrrolidine...)
Affinity DataKi:  699nMAssay Description:Inhibitory concentration of the compound against plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076220((1S,7S)-7-Amino-7-benzyl-hexahydro-pyrazolo[1,2-a]...)
Affinity DataKi:  927nMAssay Description:Inhibitory concentration of the compound against Urokinase-type plasminogen activatorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Rattus norvegicus)
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076220((1S,7S)-7-Amino-7-benzyl-hexahydro-pyrazolo[1,2-a]...)
Affinity DataKi:  978nMAssay Description:Inhibitory concentration of the compound against plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076226((1S,7S)-7-Amino-7-benzyl-hexahydro-pyrazolo[1,2-a]...)
Affinity DataKi:  2.00E+3nMAssay Description:Inhibitory concentration of the compound against thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076220((1S,7S)-7-Amino-7-benzyl-hexahydro-pyrazolo[1,2-a]...)
Affinity DataIC50:  1.20nMAssay Description:Inhibitory concentration of the compound against thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076221((S)-1-((R)-2-Amino-3-phenyl-propionyl)-pyrrolidine...)
Affinity DataIC50:  1.5nMAssay Description:Inhibitory concentration of the compound against thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076219((3S,6R)-6-Amino-6-benzyl-octahydro-indolizine-3-ca...)
Affinity DataIC50:  19.3nMAssay Description:Inhibitory concentration of the compound against Coagulation factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076219((3S,6R)-6-Amino-6-benzyl-octahydro-indolizine-3-ca...)
Affinity DataIC50:  93nMAssay Description:Inhibitory concentration of the compound against Tissue type plasminogen activatorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076219((3S,6R)-6-Amino-6-benzyl-octahydro-indolizine-3-ca...)
Affinity DataIC50:  200nMAssay Description:Inhibitory concentration of the compound against coagulation factor VIIaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Rattus norvegicus)
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076219((3S,6R)-6-Amino-6-benzyl-octahydro-indolizine-3-ca...)
Affinity DataIC50:  251nMAssay Description:Inhibitory concentration of the compound against plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076222((1S,7S)-7-Amino-7-benzyl-hexahydro-pyrazolo[1,2-a]...)
Affinity DataIC50:  270nMAssay Description:Inhibitory concentration of the compound against coagulation factor VIIaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076222((1S,7S)-7-Amino-7-benzyl-hexahydro-pyrazolo[1,2-a]...)
Affinity DataIC50:  270nMAssay Description:Inhibitory concentration of the compound against Coagulation factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076219((3S,6R)-6-Amino-6-benzyl-octahydro-indolizine-3-ca...)
Affinity DataIC50:  335nMAssay Description:Inhibitory concentration of the compound against Urokinase-type plasminogen activatorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Rattus norvegicus)
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076222((1S,7S)-7-Amino-7-benzyl-hexahydro-pyrazolo[1,2-a]...)
Affinity DataIC50:  415nMAssay Description:Inhibitory concentration of the compound against plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076222((1S,7S)-7-Amino-7-benzyl-hexahydro-pyrazolo[1,2-a]...)
Affinity DataIC50:  495nMAssay Description:Inhibitory concentration of the compound against Tissue type plasminogen activatorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076222((1S,7S)-7-Amino-7-benzyl-hexahydro-pyrazolo[1,2-a]...)
Affinity DataIC50:  600nMAssay Description:Inhibitory concentration of the compound against Urokinase-type plasminogen activatorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed