BDBM50076221 (S)-1-((R)-2-Amino-3-phenyl-propionyl)-pyrrolidine-2-carboxylic acid ((S)-1-chloromethyl-4-guanidino-butyl)-amide::CHEMBL265315

SMILES N[C@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@H](CCl)CCCNC(N)=N

InChI Key InChIKey=BRZYOTMFHLERHD-BBWFWOEESA-N

Data  5 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50076221   

TargetTissue-type plasminogen activator(Homo sapiens (Human))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076221((S)-1-((R)-2-Amino-3-phenyl-propionyl)-pyrrolidine...)
Affinity DataKi:  106nMAssay Description:Compound was evaluated for the inhibition of Tissue type plasminogen activator (tissue plasminogen activator)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076221((S)-1-((R)-2-Amino-3-phenyl-propionyl)-pyrrolidine...)
Affinity DataKi:  165nMAssay Description:Inhibitory concentration of the compound against Coagulation factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076221((S)-1-((R)-2-Amino-3-phenyl-propionyl)-pyrrolidine...)
Affinity DataKi:  200nMAssay Description:Inhibitory concentration of the compound against coagulation factor VIIaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076221((S)-1-((R)-2-Amino-3-phenyl-propionyl)-pyrrolidine...)
Affinity DataKi:  508nMAssay Description:Inhibitory concentration of the compound against Urokinase-type plasminogen activatorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Rattus norvegicus)
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076221((S)-1-((R)-2-Amino-3-phenyl-propionyl)-pyrrolidine...)
Affinity DataKi:  699nMAssay Description:Inhibitory concentration of the compound against plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076221((S)-1-((R)-2-Amino-3-phenyl-propionyl)-pyrrolidine...)
Affinity DataIC50:  1.5nMAssay Description:Inhibitory concentration of the compound against thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed