Affinity DataKi: 3.70nMAssay Description:Binding affinity at histamine H3 receptor by hH3-[35S]GTPgamma[S] binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.70nMAssay Description:Binding affinity at histamine H3 receptor by hH3-[35S]GTPgamma[S] binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 11.2nMAssay Description:Binding affinity at histamine H3 receptor by hH3-[35S]GTPgamma[S] binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 13.4nMAssay Description:Binding affinity at histamine H3 receptor by hH3-[35S]GTPgamma[S] binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:Binding affinity at histamine H3 receptor by hH3-[35S]GTPgamma[S] binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:Binding affinity at histamine H3 receptor by hH3-[35S]GTPgamma[S] binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Binding affinity at histamine H3 receptor by hH3-[35S]GTPgamma[S] binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Binding affinity at histamine H3 receptor by hH3-[35S]GTPgamma[S] binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 17nMAssay Description:Binding affinity at histamine H3 receptor by hH3-[35S]GTPgamma[S] binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Binding affinity at histamine H3 receptor by hH3-[35S]GTPgamma[S] binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 23nMAssay Description:Binding affinity at histamine H3 receptor by hH3-[35S]GTPgamma[S] binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 25nMAssay Description:Binding affinity at histamine H3 receptor by hH3-[35S]GTPgamma[S] binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 27nMAssay Description:Binding affinity at histamine H3 receptor by hH3-[35S]GTPgamma[S] binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 29nMAssay Description:Binding affinity at histamine H3 receptor by hH3-[35S]GTPgamma[S] binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:Binding affinity at histamine H3 receptor by hH3-[35S]GTPgamma[S] binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 34nMAssay Description:Binding affinity at histamine H3 receptor by hH3-[35S]GTPgamma[S] binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 34nMAssay Description:Binding affinity at histamine H3 receptor by hH3-[35S]GTPgamma[S] binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 37nMAssay Description:Binding affinity at histamine H3 receptor by hH3-[35S]GTPgamma[S] binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 38nMAssay Description:Binding affinity at histamine H3 receptor by hH3-[35S]GTPgamma[S] binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 40nMAssay Description:Binding affinity at histamine H3 receptor by hH3-[35S]GTPgamma[S] binding assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novo Nordisk
Curated by ChEMBL
Novo Nordisk
Curated by ChEMBL
Affinity DataKi: 42nMAssay Description:Displacement of [3H]Astemizole from hERG expressed in HEK293 cells at 10 uMMore data for this Ligand-Target Pair
Affinity DataKi: 44nMAssay Description:Binding affinity at histamine H3 receptor by hH3-[35S]GTPgamma[S] binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 45nMAssay Description:Binding affinity at histamine H3 receptor by hH3-[35S]GTPgamma[S] binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 47nMAssay Description:Binding affinity at histamine H3 receptor by hH3-[35S]GTPgamma[S] binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 47nMAssay Description:Binding affinity at histamine H3 receptor by hH3-[35S]GTPgamma[S] binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 52nMAssay Description:Binding affinity at histamine H3 receptor by hH3-[35S]GTPgamma[S] binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 59nMAssay Description:Binding affinity at histamine H3 receptor by hH3-[35S]GTPgamma[S] binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 73nMAssay Description:Binding affinity at histamine H3 receptor by hH3-[35S]GTPgamma[S] binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 78nMAssay Description:Binding affinity at histamine H3 receptor by hH3-[35S]GTPgamma[S] binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 86nMAssay Description:Binding affinity at histamine H3 receptor by hH3-[35S]GTPgamma[S] binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 87nMAssay Description:Binding affinity at histamine H3 receptor by hH3-[35S]GTPgamma[S] binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 94nMAssay Description:Binding affinity at histamine H3 receptor by hH3-[35S]GTPgamma[S] binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 94nMAssay Description:Binding affinity at histamine H3 receptor by hH3-[35S]GTPgamma[S] binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 109nMAssay Description:Binding affinity at histamine H3 receptor by hH3-[35S]GTPgamma[S] binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 117nMAssay Description:Binding affinity at histamine H3 receptor by hH3-[35S]GTPgamma[S] binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 121nMAssay Description:Binding affinity at histamine H3 receptor by hH3-[35S]GTPgamma[S] binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 162nMAssay Description:Binding affinity at histamine H3 receptor by hH3-[35S]GTPgamma[S] binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 165nMAssay Description:Binding affinity at histamine H3 receptor by hH3-[35S]GTPgamma[S] binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 188nMAssay Description:Binding affinity at histamine H3 receptor by hH3-[35S]GTPgamma[S] binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 196nMAssay Description:Binding affinity at histamine H3 receptor by hH3-[35S]GTPgamma[S] binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 226nMAssay Description:Binding affinity at histamine H3 receptor by hH3-[35S]GTPgamma[S] binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 281nMAssay Description:Binding affinity at histamine H3 receptor by hH3-[35S]GTPgamma[S] binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 295nMAssay Description:Binding affinity at histamine H3 receptor by hH3-[35S]GTPgamma[S] binding assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novo Nordisk
Curated by ChEMBL
Novo Nordisk
Curated by ChEMBL
Affinity DataKi: 444nMAssay Description:Displacement of [3H]Astemizole from hERG expressed in HEK293 cells at 10 uMMore data for this Ligand-Target Pair
Affinity DataKi: 458nMAssay Description:Binding affinity at histamine H3 receptor by hH3-[35S]GTPgamma[S] binding assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novo Nordisk
Curated by ChEMBL
Novo Nordisk
Curated by ChEMBL
Affinity DataKi: 512nMAssay Description:Displacement of [3H]Astemizole from hERG expressed in HEK293 cells at 10 uMMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novo Nordisk
Curated by ChEMBL
Novo Nordisk
Curated by ChEMBL
Affinity DataKi: 869nMAssay Description:Displacement of [3H]Astemizole from hERG expressed in HEK293 cells at 10 uMMore data for this Ligand-Target Pair
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of CYP2D6 in human liver microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomesMore data for this Ligand-Target Pair