BDBM50193184 CHEMBL219592::isoindolin-2-yl(4-isopropylpiperazin-1-yl)methanone

SMILES CC(C)N1CCN(CC1)C(=O)N1Cc2ccccc2C1

InChI Key InChIKey=OBOPRPJYPONXMS-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50193184   

TargetHistamine H3 receptor(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50193184(CHEMBL219592 | isoindolin-2-yl(4-isopropylpiperazi...)
Affinity DataKi:  59nMAssay Description:Binding affinity at histamine H3 receptor by hH3-[35S]GTPgamma[S] binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50193184(CHEMBL219592 | isoindolin-2-yl(4-isopropylpiperazi...)
Affinity DataKi:  59nMAssay Description:Displacement of [125I]Iodoproxyfan from human recombinant histamine H3 receptor by Competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50193184(CHEMBL219592 | isoindolin-2-yl(4-isopropylpiperazi...)
Affinity DataIC50:  1.94E+4nMAssay Description:Displacement of [3H]dofetilide from human recombinant ERG by Competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed