Compile Data Set for Download or QSAR
maximum 50k data
Found 15 Enz. Inhib. hit(s) with all data for entry = 50030552
TargetCathepsin D(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50297934(2-Hydroxy-2-phenethyl-pentanedioic acid 1-[((1S,2R...)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of human liver cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50297936(2-Hydroxy-2-phenethyl-pentanedioic acid 5-{[3-(met...)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of human liver cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50297936(2-Hydroxy-2-phenethyl-pentanedioic acid 5-{[3-(met...)
Affinity DataIC50:  230nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) using Swedish mutant sequence Eu-EVNLDAEFK-Quencher substrate by homogeneous time r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50297935(2-Hydroxy-2-phenethyl-pentanedioic acid 1-[((S)-1-...)
Affinity DataIC50:  450nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) using Swedish mutant sequence Eu-EVNLDAEFK-Quencher substrate by homogeneous time r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50297934(2-Hydroxy-2-phenethyl-pentanedioic acid 1-[((1S,2R...)
Affinity DataIC50:  570nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) using Swedish mutant sequence Eu-EVNLDAEFK-Quencher substrate by homogeneous time r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50297933((S)-2-Benzyl-2-hydroxy-pentanedioic acid 1-[((1S,2...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) using Swedish mutant sequence Eu-EVNLDAEFK-Quencher substrate by homogeneous time r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50297929(4-((S)-2-{4-[3-[(R)-1-(4-Fluoro-phenyl)-ethylcarba...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) using Swedish mutant sequence Eu-EVNLDAEFK-Quencher substrate by homogeneous time r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50297932((R)-2-Benzyl-2-hydroxy-pentanedioic acid 1-[((1S,2...)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) using Swedish mutant sequence Eu-EVNLDAEFK-Quencher substrate by homogeneous time r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50297927(2-Hydroxy-2-phenethyl-pentanedioic acid 5-[((S)-1-...)
Affinity DataIC50:  5.60E+3nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) using Swedish mutant sequence Eu-EVNLDAEFK-Quencher substrate by homogeneous time r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50297925(2-Benzyl-2-hydroxy-pentanedioic acid 5-[((S)-1-ben...)
Affinity DataIC50:  5.90E+3nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) using Swedish mutant sequence Eu-EVNLDAEFK-Quencher substrate by homogeneous time r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50297931(4-((S)-2-{4-[3-[(R)-1-(4-Fluoro-phenyl)-ethylcarba...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) using Swedish mutant sequence Eu-EVNLDAEFK-Quencher substrate by homogeneous time r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50297938(2-Benzyl-2-hydroxy-pentanedioic acid 1-{[3-[(R)-1-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) using Swedish mutant sequence Eu-EVNLDAEFK-Quencher substrate by homogeneous time r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50297928(4-[((S)-2-{4-[3-[(R)-1-(4-Fluoro-phenyl)-ethylcarb...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) using Swedish mutant sequence Eu-EVNLDAEFK-Quencher substrate by homogeneous time r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50297926(2-Hydroxy-2-phenethyl-pentanedioic acid 5-[((S)-1-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) using Swedish mutant sequence Eu-EVNLDAEFK-Quencher substrate by homogeneous time r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50297930(4-[((S)-2-{4-[3-[(R)-1-(4-Fluoro-phenyl)-ethylcarb...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) using Swedish mutant sequence Eu-EVNLDAEFK-Quencher substrate by homogeneous time r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed