BDBM50297934 2-Hydroxy-2-phenethyl-pentanedioic acid 1-[((1S,2R)-2-hydroxy-indan-1-yl)-amide]5-{[3-(methanesulfonyl-methyl-amino)-5-((R)-1-phenyl-ethylcarbamoyl)-phenyl] -amide}::2-Hydroxy-2-phenethyl-pentanedioic acid 1-[((1S,2R)-2-hydroxy-indan-1-yl)-amide]5-{[3-(methanesulfonyl-methyl-amino)-5-((R)-1-phenyl-ethylcarbamoyl)-phenyl]-amide}::CHEMBL554781

SMILES C[C@@H](NC(=O)c1cc(NC(=O)CCC(O)(CCc2ccccc2)C(=O)N[C@@H]2[C@H](O)Cc3ccccc23)cc(c1)N(C)S(C)(=O)=O)c1ccccc1

InChI Key InChIKey=XQNJAMRLHRQUHB-MLGXSISHSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50297934   

TargetCathepsin D(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50297934(2-Hydroxy-2-phenethyl-pentanedioic acid 1-[((1S,2R...)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of human liver cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50297934(2-Hydroxy-2-phenethyl-pentanedioic acid 1-[((1S,2R...)
Affinity DataIC50:  570nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) using Swedish mutant sequence Eu-EVNLDAEFK-Quencher substrate by homogeneous time r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed