Compile Data Set for Download or QSAR
maximum 50k data
Found 153 Enz. Inhib. hit(s) with all data for entry = 50007140
TargetChymase(Homo sapiens (Human))
Suntory

Curated by ChEMBL
LigandPNGBDBM50058973(3-(3,4-Dichloro-benzenesulfonyl)-1-phenyl-imidazol...)
Affinity DataIC50:  18nMAssay Description:Inhibitory activity against human heart chymase in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
Suntory

Curated by ChEMBL
LigandPNGBDBM50058984(3-(3,4-Dichloro-benzenesulfonyl)-1-(3,4-dimethyl-p...)
Affinity DataIC50:  20nMAssay Description:Inhibitory activity against human heart chymase in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
Suntory

Curated by ChEMBL
LigandPNGBDBM50058990(3-(3,4-Dimethoxy-benzenesulfonyl)-1-(3,4-dimethyl-...)
Affinity DataIC50:  22nMAssay Description:Inhibitory activity against human heart chymase in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
Suntory

Curated by ChEMBL
LigandPNGBDBM50058996(3-(4-Chloro-benzenesulfonyl)-1-(3,4-dichloro-pheny...)
Affinity DataIC50:  23nMAssay Description:Inhibitory activity against human heart chymase in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
Suntory

Curated by ChEMBL
LigandPNGBDBM50059007(4-(2,5-Dioxo-3-phenyl-imidazolidine-1-sulfonyl)-be...)
Affinity DataIC50:  29nMAssay Description:Inhibitory activity against human heart chymase in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
Suntory

Curated by ChEMBL
LigandPNGBDBM50058964(3-(3,4-Dimethyl-benzenesulfonyl)-1-phenyl-imidazol...)
Affinity DataIC50:  30nMAssay Description:Inhibitory activity against human heart chymase in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
Suntory

Curated by ChEMBL
LigandPNGBDBM50058969(3-(4-Chloro-benzenesulfonyl)-1-(3,4-dimethyl-pheny...)
Affinity DataIC50:  35nMAssay Description:Inhibitory activity against human heart chymase in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
Suntory

Curated by ChEMBL
LigandPNGBDBM50058972(4-(2,5-Dioxo-3-phenyl-imidazolidine-1-sulfonyl)-be...)
Affinity DataIC50:  40nMAssay Description:Inhibitory activity against human heart chymase in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Suntory

Curated by ChEMBL
LigandPNGBDBM50058977(3-Benzoyl-1-phenyl-imidazolidine-2,4-dione | CHEMB...)
Affinity DataIC50:  48nMAssay Description:Inhibitory activity against bovine pancreas alpha-chymotrypsin in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
Suntory

Curated by ChEMBL
LigandPNGBDBM50058999(3-(3,4-Dimethyl-benzenesulfonyl)-1-(3,4-dimethyl-p...)
Affinity DataIC50:  60nMAssay Description:Inhibitory activity against human heart chymase in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
Suntory

Curated by ChEMBL
LigandPNGBDBM50059002(3-(4-Chloro-benzenesulfonyl)-1-(3-chloro-phenyl)-i...)
Affinity DataIC50:  66nMAssay Description:Inhibitory activity against human heart chymase in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
Suntory

Curated by ChEMBL
LigandPNGBDBM50058975(3-(2,5-Dioxo-3-phenyl-imidazolidine-1-sulfonyl)-be...)
Affinity DataIC50:  68nMAssay Description:Inhibitory activity against human heart chymase in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
Suntory

Curated by ChEMBL
LigandPNGBDBM50058994(3-(2,5-Dioxo-3-phenyl-imidazolidine-1-sulfonyl)-be...)
Affinity DataIC50:  82nMAssay Description:Inhibitory activity against human heart chymase in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
Suntory

Curated by ChEMBL
LigandPNGBDBM50059014(3-(3,4-Dimethoxy-benzenesulfonyl)-1-phenyl-imidazo...)
Affinity DataIC50:  110nMAssay Description:Inhibitory activity against human heart chymase in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
Suntory

Curated by ChEMBL
LigandPNGBDBM50059000(3-(3-Chloro-benzenesulfonyl)-1-phenyl-imidazolidin...)
Affinity DataIC50:  130nMAssay Description:Inhibitory activity against human heart chymase in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
Suntory

Curated by ChEMBL
LigandPNGBDBM50059005(3-(4-Bromo-benzenesulfonyl)-1-phenyl-imidazolidine...)
Affinity DataIC50:  170nMAssay Description:Inhibitory activity against human heart chymase in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
Suntory

Curated by ChEMBL
LigandPNGBDBM50059003(3-(3,4-Dichloro-benzenesulfonyl)-1-(3,4-dichloro-p...)
Affinity DataIC50:  170nMAssay Description:Inhibitory activity against human heart chymase in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Suntory

Curated by ChEMBL
LigandPNGBDBM50059002(3-(4-Chloro-benzenesulfonyl)-1-(3-chloro-phenyl)-i...)
Affinity DataIC50:  200nMAssay Description:Inhibitory activity against bovine pancreas alpha-chymotrypsin in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin G(Homo sapiens (Human))
Suntory

Curated by ChEMBL
LigandPNGBDBM50058964(3-(3,4-Dimethyl-benzenesulfonyl)-1-phenyl-imidazol...)
Affinity DataIC50:  220nMAssay Description:Inhibitory activity against human neutrophil cathepsin G.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
Suntory

Curated by ChEMBL
LigandPNGBDBM50058982(3-(4-Chloro-benzenesulfonyl)-1-(2-chloro-phenyl)-i...)
Affinity DataIC50:  220nMAssay Description:Inhibitory activity against human heart chymase in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin G(Homo sapiens (Human))
Suntory

Curated by ChEMBL
LigandPNGBDBM50058973(3-(3,4-Dichloro-benzenesulfonyl)-1-phenyl-imidazol...)
Affinity DataIC50:  230nMAssay Description:Inhibitory activity against human neutrophil cathepsin G.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Suntory

Curated by ChEMBL
LigandPNGBDBM50059013(3-(4-Chloro-benzoyl)-1-phenyl-imidazolidine-2,4-di...)
Affinity DataIC50:  230nMAssay Description:Inhibitory activity against bovine pancreas alpha-chymotrypsin in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
Suntory

Curated by ChEMBL
LigandPNGBDBM50059011(3-(4-Chloro-benzenesulfonyl)-1-(4-chloro-phenyl)-i...)
Affinity DataIC50:  300nMAssay Description:Inhibitory activity against human heart chymase in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin G(Homo sapiens (Human))
Suntory

Curated by ChEMBL
LigandPNGBDBM50058972(4-(2,5-Dioxo-3-phenyl-imidazolidine-1-sulfonyl)-be...)
Affinity DataIC50:  330nMAssay Description:Inhibitory activity against human neutrophil cathepsin G.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin G(Homo sapiens (Human))
Suntory

Curated by ChEMBL
LigandPNGBDBM50059007(4-(2,5-Dioxo-3-phenyl-imidazolidine-1-sulfonyl)-be...)
Affinity DataIC50:  340nMAssay Description:Inhibitory activity against human neutrophil cathepsin G.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
Suntory

Curated by ChEMBL
LigandPNGBDBM50058998(3-(4-Fluoro-benzenesulfonyl)-1-phenyl-imidazolidin...)
Affinity DataIC50:  370nMAssay Description:Inhibitory activity against human heart chymase in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
Suntory

Curated by ChEMBL
LigandPNGBDBM50059012(3-(4-Chloro-benzenesulfonyl)-1-phenyl-imidazolidin...)
Affinity DataIC50:  380nMAssay Description:Inhibitory activity against human heart chymase in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Suntory

Curated by ChEMBL
LigandPNGBDBM50059011(3-(4-Chloro-benzenesulfonyl)-1-(4-chloro-phenyl)-i...)
Affinity DataIC50:  500nMAssay Description:Inhibitory activity against bovine pancreas alpha-chymotrypsin in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
Suntory

Curated by ChEMBL
LigandPNGBDBM50058971(CHEMBL304338 | [3-(2,5-Dioxo-3-phenyl-imidazolidin...)
Affinity DataIC50:  500nMAssay Description:Inhibitory activity against human heart chymase in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
Suntory

Curated by ChEMBL
LigandPNGBDBM50059006(3-(4-Methoxy-benzenesulfonyl)-1-phenyl-imidazolidi...)
Affinity DataIC50:  550nMAssay Description:Inhibitory activity against human heart chymase in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
Suntory

Curated by ChEMBL
LigandPNGBDBM50058983(3-(3-Methoxy-benzenesulfonyl)-1-phenyl-imidazolidi...)
Affinity DataIC50:  580nMAssay Description:Inhibitory activity against human heart chymase in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin G(Homo sapiens (Human))
Suntory

Curated by ChEMBL
LigandPNGBDBM50059005(3-(4-Bromo-benzenesulfonyl)-1-phenyl-imidazolidine...)
Affinity DataIC50:  600nMAssay Description:Inhibitory activity against human neutrophil cathepsin G.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin G(Homo sapiens (Human))
Suntory

Curated by ChEMBL
LigandPNGBDBM50058994(3-(2,5-Dioxo-3-phenyl-imidazolidine-1-sulfonyl)-be...)
Affinity DataIC50:  640nMAssay Description:Inhibitory activity against human neutrophil cathepsin G.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
Suntory

Curated by ChEMBL
LigandPNGBDBM50058966(3-(4-Phenoxy-benzenesulfonyl)-1-phenyl-imidazolidi...)
Affinity DataIC50:  700nMAssay Description:Inhibitory activity against human heart chymase in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin G(Homo sapiens (Human))
Suntory

Curated by ChEMBL
LigandPNGBDBM50059012(3-(4-Chloro-benzenesulfonyl)-1-phenyl-imidazolidin...)
Affinity DataIC50:  700nMAssay Description:Inhibitory activity against human neutrophil cathepsin G.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
Suntory

Curated by ChEMBL
LigandPNGBDBM50058989(3-(4-Nitro-benzenesulfonyl)-1-phenyl-imidazolidine...)
Affinity DataIC50:  700nMAssay Description:Inhibitory activity against human heart chymase in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Suntory

Curated by ChEMBL
LigandPNGBDBM50058975(3-(2,5-Dioxo-3-phenyl-imidazolidine-1-sulfonyl)-be...)
Affinity DataIC50:  730nMAssay Description:Inhibitory activity against bovine pancreas alpha-chymotrypsin in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin G(Homo sapiens (Human))
Suntory

Curated by ChEMBL
LigandPNGBDBM50058975(3-(2,5-Dioxo-3-phenyl-imidazolidine-1-sulfonyl)-be...)
Affinity DataIC50:  780nMAssay Description:Inhibitory activity against human neutrophil cathepsin G.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
Suntory

Curated by ChEMBL
LigandPNGBDBM50058967(3-(3-Phenoxy-benzenesulfonyl)-1-phenyl-imidazolidi...)
Affinity DataIC50:  800nMAssay Description:Inhibitory activity against human heart chymase in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
Suntory

Curated by ChEMBL
LigandPNGBDBM50058979(3-(2,5-Dioxo-3-phenyl-imidazolidine-1-sulfonyl)-be...)
Affinity DataIC50:  860nMAssay Description:Inhibitory activity against human heart chymase in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
Suntory

Curated by ChEMBL
LigandPNGBDBM50058965(3-[3-(4-Methyl-piperazine-1-carbonyl)-benzenesulfo...)
Affinity DataIC50:  900nMAssay Description:Inhibitory activity against human heart chymase in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin G(Homo sapiens (Human))
Suntory

Curated by ChEMBL
LigandPNGBDBM50058979(3-(2,5-Dioxo-3-phenyl-imidazolidine-1-sulfonyl)-be...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibitory activity against human neutrophil cathepsin G.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Suntory

Curated by ChEMBL
LigandPNGBDBM50059012(3-(4-Chloro-benzenesulfonyl)-1-phenyl-imidazolidin...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibitory activity against bovine pancreas alpha-chymotrypsin in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
Suntory

Curated by ChEMBL
LigandPNGBDBM50058993(3-(2-Chloro-benzenesulfonyl)-1-phenyl-imidazolidin...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibitory activity against human heart chymase in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Suntory

Curated by ChEMBL
LigandPNGBDBM50058997(1-Phenyl-3-(toluene-2-sulfonyl)-imidazolidine-2,4-...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibitory activity against bovine pancreas alpha-chymotrypsin in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Suntory

Curated by ChEMBL
LigandPNGBDBM50058993(3-(2-Chloro-benzenesulfonyl)-1-phenyl-imidazolidin...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibitory activity against bovine pancreas alpha-chymotrypsin in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Suntory

Curated by ChEMBL
LigandPNGBDBM50058967(3-(3-Phenoxy-benzenesulfonyl)-1-phenyl-imidazolidi...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibitory activity against bovine pancreas alpha-chymotrypsin in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Suntory

Curated by ChEMBL
LigandPNGBDBM50059009(3-Benzenesulfonyl-1-phenyl-imidazolidine-2,4-dione...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibitory activity against bovine pancreas alpha-chymotrypsin in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Suntory

Curated by ChEMBL
LigandPNGBDBM50058965(3-[3-(4-Methyl-piperazine-1-carbonyl)-benzenesulfo...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibitory activity against bovine pancreas alpha-chymotrypsin in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin G(Homo sapiens (Human))
Suntory

Curated by ChEMBL
LigandPNGBDBM50058998(3-(4-Fluoro-benzenesulfonyl)-1-phenyl-imidazolidin...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibitory activity against human neutrophil cathepsin G.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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