Compile Data Set for Download or QSAR
maximum 50k data
Found 42 Enz. Inhib. hit(s) with all data for entry = 50026972
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50265086((+/-)-2-amino-N-(2-(1-methyl-4-(4-(methylthio)benz...)
Affinity DataIC50:  0.950nMAssay Description:Displacement of radiolabeled MCP1 from CCR2 in human PBMC by millipore filter plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50265204((+/-)-2-amino-N-(2-(1-methyl-4-(4-(methylthio)benz...)
Affinity DataIC50:  1.80nMAssay Description:Displacement of radiolabeled MCP1 from CCR2 in human PBMC by millipore filter plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50265087((+/-)-2-amino-N-(2-(4-(4-(methylthio)benzylamino)-...)
Affinity DataIC50:  2nMAssay Description:Antagonist activity at CCR2 in human PBMC assessed as MCP1-induced calcium flux by fluorescence-imaging plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50265204((+/-)-2-amino-N-(2-(1-methyl-4-(4-(methylthio)benz...)
Affinity DataIC50:  2nMAssay Description:Antagonist activity at CCR2 in human PBMC assessed as MCP1-induced calcium flux by fluorescence-imaging plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50265121((+/-)-N-(2-(4-(4-(methylthio)benzylamino)-1-propyl...)
Affinity DataIC50:  3nMAssay Description:Antagonist activity at CCR2 in human PBMC assessed as MCP1-induced calcium flux by fluorescence-imaging plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50265123((+/-)-3-amino-N-(2-(4-(4-(methylthio)benzylamino)-...)
Affinity DataIC50:  3nMAssay Description:Antagonist activity at CCR2 in human PBMC assessed as MCP1-induced calcium flux by fluorescence-imaging plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50265087((+/-)-2-amino-N-(2-(4-(4-(methylthio)benzylamino)-...)
Affinity DataIC50:  3.40nMAssay Description:Displacement of radiolabeled MCP1 from CCR2 in human PBMC by millipore filter plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50265121((+/-)-N-(2-(4-(4-(methylthio)benzylamino)-1-propyl...)
Affinity DataIC50:  3.80nMAssay Description:Displacement of radiolabeled MCP1 from CCR2 in human PBMC by millipore filter plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50265203((+/-)-2-amino-N-(2-(1-butyl-4-(4-(methylthio)benza...)
Affinity DataIC50:  4.30nMAssay Description:Displacement of radiolabeled MCP1 from CCR2 in human PBMC by millipore filter plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50265122((+/-)-N-(2-(2-(4-(4-(methylthio)benzylamino)-1-pro...)
Affinity DataIC50:  4.80nMAssay Description:Antagonist activity at CCR2 in human PBMC assessed as MCP1-induced chemotaxisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50265086((+/-)-2-amino-N-(2-(1-methyl-4-(4-(methylthio)benz...)
Affinity DataIC50:  5nMAssay Description:Antagonist activity at CCR2 in human PBMC assessed as MCP1-induced calcium flux by fluorescence-imaging plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50265087((+/-)-2-amino-N-(2-(4-(4-(methylthio)benzylamino)-...)
Affinity DataIC50:  5.40nMAssay Description:Antagonist activity at CCR2 in human PBMC assessed as MCP1-induced chemotaxisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50265205((+/-)-3-amino-N-(2-(4-(4-(methylthio)benzamido)-1-...)
Affinity DataIC50:  6nMAssay Description:Antagonist activity at CCR2 in human PBMC assessed as MCP1-induced calcium flux by fluorescence-imaging plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50265123((+/-)-3-amino-N-(2-(4-(4-(methylthio)benzylamino)-...)
Affinity DataIC50:  6.10nMAssay Description:Displacement of radiolabeled MCP1 from CCR2 in human PBMC by millipore filter plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50265043((+/-)-2-amino-N-(2-(4-(4-(methylthio)benzylamino)p...)
Affinity DataIC50:  6.10nMAssay Description:Binding affinity to wild type CCR2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50265205((+/-)-3-amino-N-(2-(4-(4-(methylthio)benzamido)-1-...)
Affinity DataIC50:  6.20nMAssay Description:Displacement of radiolabeled MCP1 from CCR2 in human PBMC by millipore filter plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50265043((+/-)-2-amino-N-(2-(4-(4-(methylthio)benzylamino)p...)
Affinity DataIC50:  6.30nMAssay Description:Displacement of radiolabeled MCP1 from CCR2 in human PBMC by millipore filter plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50265043((+/-)-2-amino-N-(2-(4-(4-(methylthio)benzylamino)p...)
Affinity DataIC50:  7nMAssay Description:Antagonist activity at CCR2 in human PBMC assessed as MCP1-induced calcium flux by fluorescence-imaging plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50265120((+/-)-2-amino-N-(2-(1-butyl-4-(4-(methylthio)benzy...)
Affinity DataIC50:  7.90nMAssay Description:Displacement of radiolabeled MCP1 from CCR2 in human PBMC by millipore filter plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50265121((+/-)-N-(2-(4-(4-(methylthio)benzylamino)-1-propyl...)
Affinity DataIC50:  8nMAssay Description:Antagonist activity at CCR2 in human PBMC assessed as MCP1-induced chemotaxisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50265122((+/-)-N-(2-(2-(4-(4-(methylthio)benzylamino)-1-pro...)
Affinity DataIC50:  8.70nMAssay Description:Displacement of radiolabeled MCP1 from CCR2 in human PBMC by millipore filter plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50255735((+/-)-2-amino-N-(2-(4-(4-(methylthio)benzamido)pip...)
Affinity DataIC50:  12nMAssay Description:Binding affinity to wild type CCR2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50265120((+/-)-2-amino-N-(2-(1-butyl-4-(4-(methylthio)benzy...)
Affinity DataIC50:  13nMAssay Description:Antagonist activity at CCR2 in human PBMC assessed as MCP1-induced calcium flux by fluorescence-imaging plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50265203((+/-)-2-amino-N-(2-(1-butyl-4-(4-(methylthio)benza...)
Affinity DataIC50:  13nMAssay Description:Antagonist activity at CCR2 in human PBMC assessed as MCP1-induced calcium flux by fluorescence-imaging plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50265203((+/-)-2-amino-N-(2-(1-butyl-4-(4-(methylthio)benza...)
Affinity DataIC50:  17.5nMAssay Description:Antagonist activity at CCR2 in human PBMC assessed as MCP1-induced chemotaxisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50265044((+/-)-2-amino-N-(2-(4-(4-chlorobenzylamino)piperid...)
Affinity DataIC50:  19nMAssay Description:Antagonist activity at CCR2 in human PBMC assessed as MCP1-induced calcium flux by fluorescence-imaging plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50265120((+/-)-2-amino-N-(2-(1-butyl-4-(4-(methylthio)benzy...)
Affinity DataIC50:  19nMAssay Description:Antagonist activity at CCR2 in human PBMC assessed as MCP1-induced chemotaxisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50265122((+/-)-N-(2-(2-(4-(4-(methylthio)benzylamino)-1-pro...)
Affinity DataIC50:  21nMAssay Description:Antagonist activity at CCR2 in human PBMC assessed as MCP1-induced calcium flux by fluorescence-imaging plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50265044((+/-)-2-amino-N-(2-(4-(4-chlorobenzylamino)piperid...)
Affinity DataIC50:  21.5nMAssay Description:Displacement of radiolabeled MCP1 from CCR2 in human PBMC by millipore filter plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50265205((+/-)-3-amino-N-(2-(4-(4-(methylthio)benzamido)-1-...)
Affinity DataIC50:  25nMAssay Description:Antagonist activity at CCR2 in human PBMC assessed as MCP1-induced chemotaxisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50265123((+/-)-3-amino-N-(2-(4-(4-(methylthio)benzylamino)-...)
Affinity DataIC50:  26nMAssay Description:Antagonist activity at CCR2 in human PBMC assessed as MCP1-induced chemotaxisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50265086((+/-)-2-amino-N-(2-(1-methyl-4-(4-(methylthio)benz...)
Affinity DataIC50:  27.5nMAssay Description:Antagonist activity at CCR2 in human PBMC assessed as MCP1-induced chemotaxisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50255735((+/-)-2-amino-N-(2-(4-(4-(methylthio)benzamido)pip...)
Affinity DataIC50:  28nMAssay Description:Displacement of radiolabeled MCP1 from CCR2 in human PBMC by millipore filter plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50265204((+/-)-2-amino-N-(2-(1-methyl-4-(4-(methylthio)benz...)
Affinity DataIC50:  38.5nMAssay Description:Antagonist activity at CCR2 in human PBMC assessed as MCP1-induced chemotaxisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50255735((+/-)-2-amino-N-(2-(4-(4-(methylthio)benzamido)pip...)
Affinity DataIC50:  75nMAssay Description:Antagonist activity at CCR2 in human PBMC assessed as MCP1-induced calcium flux by fluorescence-imaging plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50265085((+/-)-N-(2-(4-(4-(methylthio)benzylamino)piperidin...)
Affinity DataIC50:  97nMAssay Description:Displacement of radiolabeled MCP1 from CCR2 in human PBMC by millipore filter plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50255735((+/-)-2-amino-N-(2-(4-(4-(methylthio)benzamido)pip...)
Affinity DataIC50:  109nMAssay Description:Antagonist activity at CCR2 in human PBMC assessed as MCP1-induced chemotaxisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50265084((+/-)-2-amino-N-(2-(4-(4-(ethylthio)benzylamino)pi...)
Affinity DataIC50:  123nMAssay Description:Displacement of radiolabeled MCP1 from CCR2 in human PBMC by millipore filter plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50265043((+/-)-2-amino-N-(2-(4-(4-(methylthio)benzylamino)p...)
Affinity DataIC50:  285nMAssay Description:Antagonist activity at CCR2 in human PBMC assessed as MCP1-induced chemotaxisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50265164((+/-)-N-(2-(1-acetyl-4-(4-(methylthio)benzylamino)...)
Affinity DataIC50:  463nMAssay Description:Displacement of radiolabeled MCP1 from CCR2 in human PBMC by millipore filter plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50265085((+/-)-N-(2-(4-(4-(methylthio)benzylamino)piperidin...)
Affinity DataIC50:  510nMAssay Description:Antagonist activity at CCR2 in human PBMC assessed as MCP1-induced calcium flux by fluorescence-imaging plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50265042((+/-)-2-amino-N-(2-(2-(4-(methylthio)benzylamino)c...)
Affinity DataIC50:  1.18E+3nMAssay Description:Displacement of radiolabeled MCP1 from CCR2 in human PBMC by millipore filter plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed