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Target
Vasopressin V2 receptor
Ligand
BDBM50020699
Substrate
n/a
Meas. Tech.
ChEBML_214869
Ki
9200±n/a nM
Citation
 Bryan, WM; Hempel, JC; Huffman, WF; Marshall, GR; Moore, ML; Silvestri, J; Stassen, FL; Stefankiewicz, JS; Sulat, L; Webb, RL Design, synthesis, and biological activity of a peptide mimic of vasopressin. J Med Chem 31:742-4 (1988) [PubMed]  Article 
Target
Name:
Vasopressin V2 receptor
Synonyms:
AVPR2 | V2R_PIG
Type:
PROTEIN
Mol. Mass.:
40556.17
Organism:
Sus scrofa
Description:
ChEMBL_214870
Residue:
370
Sequence:
MLRATTSAVPRALSWPAAPGNGSEREPLDDRDPLLARVELALLSTVFVAVALSNGLVLGALVRRGRRGRWAPMHVFIGHLCLADLAVALFQVLPQLAWDATYRFRGPDALCRAVKYLQMVGMYASSYMILAMTLDRHRAICRPMLAYRHGGGARWNRPVLVAWAFSLLLSLPQLFIFAQRDVGDGSGVLDCWASFAEPWGLRAYVTWIALMVFVAPALGIAACQVLIFREIHTSLVPGPAERAGGHRGGRRAGSPREGARVSAAMAKTARMTLVIVAVYVLCWAPFFLVQLWSVWDPKAPREGPPFVLLMLLASLNSCTNPWIYASFSSSISSELRSLLCCPRRRTPPSLRPQEESCATASSFSARDTSS
  
Inhibitor
Name:
BDBM50020699
Synonyms:
1-(2,5-Dibenzyl-11-carbamoylmethyl-8-isopropyl-3,6,9,12,18-pentaoxo-1,4,7,10,13pentaaza-cyclooctadecane-14-carbonyl)-pyrrolidine-2-carboxylic acid [1-(carbamoylmethyl-carbamoyl)-4-guanidino-butyl]-amide | CHEMBL2371442
Type:
Small organic molecule
Emp. Form.:
C46H65N13O10
Mol. Mass.:
960.0894
SMILES:
CC(C)[C@@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)CCC[C@@H](NC(=O)[C@H](CC(N)=O)NC1=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C(N)N)C(=O)NCC(N)=O
Structure:
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