Reaction Details Report a problem with these data
Target
Adenosine receptor A1
Ligand
BDBM50124121
Substrate
n/a
Meas. Tech.
ChEBML_29472
Ki
1350±n/a nM
Citation
 Lim, MH; Kim, HO; Moon, HR; Lee, SJ; Chun, MW; Gao, ZG; Melman, N; Jacobson, KA; Kim, JH; Jeong, LS Design, synthesis and binding affinity of 3'-fluoro analogues of Cl-IB-MECA as adenosine A3 receptor ligands. Bioorg Med Chem Lett 13:817-20 (2003) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
AA1R_RAT | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | Adenosine A1 receptor (A1) | Adenosine receptor | Adenosine receptors A1 | Adora1
Type:
Protein
Mol. Mass.:
36704.13
Organism:
Rattus norvegicus (rat)
Description:
n/a
Residue:
326
Sequence:
MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED
  
Inhibitor
Name:
BDBM50124121
Synonyms:
2-{2-chloro-6-[(3-iodobenzyl)amino]-9H-purin-9-yl}-4-fluoro-5-(hydroxymethyl)tetrahydrofuran-3-ol | CHEMBL168567
Type:
Small organic molecule
Emp. Form.:
C17H16ClFIN5O3
Mol. Mass.:
519.697
SMILES:
OCC1OC(C(O)C1F)n1cnc2c(NCc3cccc(I)c3)nc(Cl)nc12
Structure:
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