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Report error Found 10 Enz. Inhib. hit(s) for PDB: 1C88
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Inha University

Curated by ChEMBL
LigandPNGBDBM50118792(2-(carboxyformamido)-4,5,6,7-tetrahydrothieno[2,3-...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of PTP1B after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Inha University

Curated by ChEMBL
LigandPNGBDBM50118792(2-(carboxyformamido)-4,5,6,7-tetrahydrothieno[2,3-...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of PTP1B after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Inha University

Curated by ChEMBL
LigandPNGBDBM50118792(2-(carboxyformamido)-4,5,6,7-tetrahydrothieno[2,3-...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of PTP1B by pNPP hydrolase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Inha University

Curated by ChEMBL
LigandPNGBDBM50118792(2-(carboxyformamido)-4,5,6,7-tetrahydrothieno[2,3-...)
Affinity DataKi:  230nMAssay Description:Inhibition of PTP1B I219A mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Inha University

Curated by ChEMBL
LigandPNGBDBM50118792(2-(carboxyformamido)-4,5,6,7-tetrahydrothieno[2,3-...)
Affinity DataKi:  290nMpH: 5.5Assay Description:Inhibitory effect against recombinant human protein-tyrosine phosphatase 1B (PTP1B), using p-nitrophenyl phosphate substrate at pH 5.5.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Inha University

Curated by ChEMBL
LigandPNGBDBM50118792(2-(carboxyformamido)-4,5,6,7-tetrahydrothieno[2,3-...)
Affinity DataKi:  290nMAssay Description:Inhibition of PTP1B (1 to 321 residues) (unknown origin) expressed in Escherichia coli BL21 assessed as inhibition constant using pNPP as substrate i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Inha University

Curated by ChEMBL
LigandPNGBDBM50118792(2-(carboxyformamido)-4,5,6,7-tetrahydrothieno[2,3-...)
Affinity DataKi:  4.70E+3nMAssay Description:Inhibition of human recombinant Protein-tyrosine phosphatase 1B.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Inha University

Curated by ChEMBL
LigandPNGBDBM50118792(2-(carboxyformamido)-4,5,6,7-tetrahydrothieno[2,3-...)
Affinity DataKi:  6.00E+3nMAssay Description:Inhibition of wild type PTP1BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Inha University

Curated by ChEMBL
LigandPNGBDBM50118792(2-(carboxyformamido)-4,5,6,7-tetrahydrothieno[2,3-...)
Affinity DataKi:  1.15E+4nMAssay Description:Inhibition of PTP1B after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Inha University

Curated by ChEMBL
LigandPNGBDBM50118792(2-(carboxyformamido)-4,5,6,7-tetrahydrothieno[2,3-...)
Affinity DataKi:  5.01E+4nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)