Found 10 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein phosphatase non-receptor type 1' and Ligand = 'BDBM50118792'
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Amherst College
Curated by ChEMBL
Amherst College
Curated by ChEMBL
Affinity DataKi: 230nMAssay Description:Inhibition of PTP1B I219A mutantMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Amherst College
Curated by ChEMBL
Amherst College
Curated by ChEMBL
Affinity DataKi: 290nMpH: 5.5Assay Description:Inhibitory effect against recombinant human protein-tyrosine phosphatase 1B (PTP1B), using p-nitrophenyl phosphate substrate at pH 5.5.More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Amherst College
Curated by ChEMBL
Amherst College
Curated by ChEMBL
Affinity DataKi: 290nMAssay Description:Inhibition of PTP1B (1 to 321 residues) (unknown origin) expressed in Escherichia coli BL21 assessed as inhibition constant using pNPP as substrate i...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Amherst College
Curated by ChEMBL
Amherst College
Curated by ChEMBL
Affinity DataKi: 4.70E+3nMAssay Description:Inhibition of human recombinant Protein-tyrosine phosphatase 1B.More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Amherst College
Curated by ChEMBL
Amherst College
Curated by ChEMBL
Affinity DataKi: 6.00E+3nMAssay Description:Inhibition of wild type PTP1BMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Amherst College
Curated by ChEMBL
Amherst College
Curated by ChEMBL
Affinity DataKi: 1.15E+4nMAssay Description:Inhibition of PTP1B after 10 minsMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Amherst College
Curated by ChEMBL
Amherst College
Curated by ChEMBL
Affinity DataKi: 5.01E+4nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Amherst College
Curated by ChEMBL
Amherst College
Curated by ChEMBL
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of PTP1B after 10 minsMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Amherst College
Curated by ChEMBL
Amherst College
Curated by ChEMBL
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of PTP1B by pNPP hydrolase assayMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Amherst College
Curated by ChEMBL
Amherst College
Curated by ChEMBL
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of PTP1B after 10 minsMore data for this Ligand-Target Pair