Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) for PDB: 2O64
TargetSerine/threonine-protein kinase pim-1(Human)
Loma Linda University School of Medicine

Curated by ChEMBL
LigandPNGBDBM23408(2-(3,4-dihydroxyphenyl)-3,5,6,7-tetrahydroxy-4H-ch...)
Affinity DataIC50: 339nMAssay Description:Inhibition of PIM1 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase pim-1(Human)
Loma Linda University School of Medicine

Curated by ChEMBL
LigandPNGBDBM23408(2-(3,4-dihydroxyphenyl)-3,5,6,7-tetrahydroxy-4H-ch...)
Affinity DataIC50: 340nMAssay Description:Inhibition of Pim1 assessed as [32P] incorporation preincubated for 15 mins before ATP substrate addition by coupled spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase pim-1(Human)
Loma Linda University School of Medicine

Curated by ChEMBL
LigandPNGBDBM23408(2-(3,4-dihydroxyphenyl)-3,5,6,7-tetrahydroxy-4H-ch...)
Affinity DataIC50: 340nMpH: 7.0 T: 2°CAssay Description:The 96-well flat-bottomed plates were coated with recombinant GST-BAD. After the plates were blocked, the reaction buffer containing test compound an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase pim-1(Human)
Loma Linda University School of Medicine

Curated by ChEMBL
LigandPNGBDBM23408(2-(3,4-dihydroxyphenyl)-3,5,6,7-tetrahydroxy-4H-ch...)
Affinity DataIC50: 340nMAssay Description:No assay is defined.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2023
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase pim-1(Human)
Loma Linda University School of Medicine

Curated by ChEMBL
LigandPNGBDBM23408(2-(3,4-dihydroxyphenyl)-3,5,6,7-tetrahydroxy-4H-ch...)
Affinity DataIC50: 340nMAssay Description:Inhibition of recombinant PIM1 (unknown origin) expressed in Escherichia coli after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase pim-1(Human)
Loma Linda University School of Medicine

Curated by ChEMBL
LigandPNGBDBM23408(2-(3,4-dihydroxyphenyl)-3,5,6,7-tetrahydroxy-4H-ch...)
Affinity DataIC50: 3.20E+5nMAssay Description:Inhibition of PIM-1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMedPDB3D3D Structure (crystal)