PMID

Data

Article Title

Organization

Anti-inflammatory tetraquinane diterpenoids from a Crinipellis species.

University of Kaiserslautern

Optimization of pyrazole-containing 1,2,4-triazolo-[3,4-b]thiadiazines, a new class of STAT3 pathway inhibitors.

University of Pittsburgh

2-Guanidinoquinazolines as new inhibitors of the STAT3 pathway.

University of Pittsburgh

Anti-inflammatory drimane sesquiterpene lactones from an Aspergillus species.

Institute of Biotechnology and Drug Research (Ibwf)

Direct interaction of garcinol and related polyisoprenylated benzophenones of Garcinia cambogia fruits with the transcription factor STAT-1 as a likely mechanism of their inhibitory effect on cytokine signaling pathways.

Universit£

Inhibiting aberrant signal transducer and activator of transcription protein activation with tetrapodal, small molecule Src homology 2 domain binders: promising agents against multiple myeloma.

University of Toronto Mississauga

Small molecule inhibitors of signal transducer and activator of transcription 3 (Stat3) protein.

University of Southern California

Small molecule STAT5-SH2 domain inhibitors exhibit potent antileukemia activity.

University of Toronto

Selectivity through Targeted Protein Degradation (TPD).

Astrazeneca

Rational drug design of benzothiazole-based derivatives as potent signal transducer and activator of transcription 3 (STAT3) signaling pathway inhibitors.

Fudan University

SD-91 as A Potent and Selective STAT3 Degrader Capable of Achieving Complete and Long-Lasting Tumor Regression.

University of Michigan

Structure-Based Discovery of SD-36 as a Potent, Selective, and Efficacious PROTAC Degrader of STAT3 Protein.

TBA

A small-molecule screen identifies the antitrypanosomal agent suramin and analogues NF023 and NF449 as inhibitors of STAT5a/b.

Leipzig University

Selective chemical probe inhibitor of Stat3, identified through structure-based virtual screening, induces antitumor activity.

University of Central Florida College of Medicine

An oxazole-based small-molecule Stat3 inhibitor modulates Stat3 stability and processing and induces antitumor cell effects.

University of Central Florida College of Medicine