BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 2.8M data for 1.2M Compounds and 9.2K Targets. Of those, 1,346K data for 622K Compounds and 4.5K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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19 articles for thisTarget

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
(+/-) 3-Amino-6-carboxamido-1,2,3,4-tetrahydrocarbazole: a conformationally restricted analogue of 5-carboxamidotryptamine with selectivity for the serotonin 5-HT1D receptor.EBI
Smithkline Beecham Pharmaceuticals
Pharmacological evaluation of a diarylmethylene-piperidine derivative: a new potent atypical antipsychotic?EBI
Ucb Pharma
First tricyclic oximino derivatives as 5-HT3 ligands.EBI
Universit£
Pyrrolizidine esters and amides as 5-HT4 receptor agonists and antagonists.EBI
Pfizer
Azaadamantane benzamide 5-HT4 agonists: gastrointestinal prokinetic SC-54750.EBI
Pfizer
Higher-end serotonin receptors: 5-HT(5), 5-HT(6), and 5-HT(7).EBI
Virginia Commonwealth University
 
(Dipropylamino)-tetrahydronaphthofurans: centrally acting serotonin agonists and dopamine agonists-antagonistsEBI
TBA
 
Serotonin 5-HT4 agonist activity of a series of meso-azanoradamantane benzamidesEBI
TBA
 
The synthesis and biological activity of some known and putative metabolites of the atypical antipsychotic agent olanzapine (LY170053)EBI
TBA
 
5-O-Carboxymethyl piperazide derivatives of serotonin: a new class of potent and selective 5-HT1D receptor agonistsEBI
TBA
 
The discovery of CP-96,021 and CP-96,486, balanced, combined, potent and orally active leukotriene D4 (LTD4)/platelet activating factor (PAF) receptor antagonists.EBI
TBA
 
Novel conformationally restricted aromatic piperidines as selective sigma receptor ligandsEBI
TBA
 
Novel ether derivatives of alkyl piperidines as potential sigma / 5HT2 antipsychotic agentsEBI
TBA
Bridgehead-methyl analog of SC-53116 as a 5-HT4 agonist.EBI
Pfizer
1H-Pyrazolo-[3,4-c]cyclophepta[1,2-c]thiophenes: a unique structural class of dopamine D4 selective ligands.EBI
Neurogen
Novel phenylpiperazine derivatives as dual cytokine regulators with TNF-alpha suppressing and IL-10 augmenting activity.EBI
Yoshitomi Pharmaceutical Industries
Conformational properties of semirigid antipsychotic drugs: the pharmacophore for dopamine D-2 antagonist activity.EBI
Harvard Medical School
Novel indolodioxanes with antihypertensive effects: potent ligands for the 5-HT1A receptor.EBI
Upjohn