Binding Database

The following articles (labelled with PubMed ID or TBD) are for your review

PMID

Data

Article Title

Organization

Identification of Triazolothiadiazoles as Potent Inhibitors of the dCTP Pyrophosphatase 1.

Karolinska Institutet

Non-kinase targets of protein kinase inhibitors.

The University of Sydney

MutT Homolog 1 (MTH1): The Silencing of a Target.

Nerviano Medical Sciences

Identification of potent and selective MTH1 inhibitors.

Md Anderson Cancer Center

Potent and Selective Inhibitors of MTH1 Probe Its Role in Cancer Cell Survival.

Astrazeneca

Ligand retargeting by binding site analogy.

University of Zurich

Discovery of Potent and Selective MTH1 Inhibitors for Oncology: Enabling Rapid Target (In)Validation.

Gilead Sciences

Discovery of a new class of MTH1 inhibitor by X-ray crystallographic screening.

University of Toyama

Creation of a Novel Class of Potent and Selective MutT Homologue 1 (MTH1) Inhibitors Using Fragment-Based Screening and Structure-Based Drug Design.

Sprint Bioscience

Fragment-Based Discovery and Optimization of Enzyme Inhibitors by Docking of Commercial Chemical Space.

Stockholm University