BDBM35554 thiophene scaffold, 21

SMILES CC(C)N(C(=O)[C@H]1CC[C@H](C)CC1)c1cc(sc1C(O)=O)-c1ccccc1

InChI Key InChIKey=RZXQBIKGWSLVEK-JCNLHEQBSA-N

Data  8 IC50  2 Kd

PDB links: 2 PDB IDs match this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 35554   

TargetGenome polyprotein(Hepatitis C virus genotype 1b (strain HC-J4) (HCV))
Idenix Sarl, An Msd

Curated by ChEMBL

LigandBDBM35554(thiophene scaffold, 21)Copy SMILESCopy InChI

Affinity DataIC50:  35nMAssay Description:Inhibition of HCV genotype 1b J4 NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
B.MOADDrugBankGoogleScholar

Ligand InfoMMDBPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
Copy BDB DOI

TargetRNA-directed RNA polymerase(Hepatitis C virus)
Idenix Sarl, An Msd

Curated by ChEMBL

LigandBDBM35554(thiophene scaffold, 21)Copy SMILESCopy InChI

Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of HCV NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/TrEMBL
B.MOADGoogleScholar

Ligand InfoMMDBPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI