BDBM35554 thiophene scaffold, 21
SMILES CC(C)N(C(=O)[C@H]1CC[C@H](C)CC1)c1cc(sc1C(O)=O)-c1ccccc1
InChI Key InChIKey=RZXQBIKGWSLVEK-JCNLHEQBSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 35554
Affinity DataIC50: 9nMpH: 7.5 T: 2°CAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
TargetGenome polyprotein [2420-2989,P2914A,R2963Q](Hepatitis C virus genotype 1b (isolate BK) (HCV))
Irbm, Mrl Rome
Irbm, Mrl Rome
Affinity DataIC50: 40nMpH: 7.5 T: 2°CAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
TargetGenome polyprotein [2420-2989,R2920E,R2963Q](Hepatitis C virus genotype 1b (isolate BK) (HCV))
Irbm, Mrl Rome
Irbm, Mrl Rome
Affinity DataIC50: 100nMpH: 7.5 T: 2°CAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
TargetGenome polyprotein [2420-2989,M2842K,R2963Q](Hepatitis C virus genotype 1b (isolate BK) (HCV))
Irbm, Mrl Rome
Irbm, Mrl Rome
Affinity DataIC50: >500nMpH: 7.5 T: 2°CAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
TargetGenome polyprotein [2420-2989,M2833T,R2963Q](Hepatitis C virus genotype 1b (isolate BK) (HCV))
Irbm, Mrl Rome
Irbm, Mrl Rome
Affinity DataIC50: 16nMpH: 7.5 T: 2°CAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair