BDBM50000296 CHEMBL441765::CHEMBL482811::U-50488H::US11492374, ID 1
SMILES CN([C@@H]1CCCC[C@H]1N1CCCC1)C(=O)Cc1ccc(Cl)c(Cl)c1
InChI Key InChIKey=VQLPLYSROCPWFF-QZTJIDSGSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 19 hits for monomerid = 50000296
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Harvard Medical School
Curated by ChEMBL
Harvard Medical School
Curated by ChEMBL
Affinity DataKi: 0.360nMAssay Description:Binding affinity towards Opioid receptor kappa 1 in guinea pig brain membranes using [3H]U-69593 as radioligandMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Harvard Medical School
Curated by ChEMBL
Harvard Medical School
Curated by ChEMBL
Affinity DataKi: 0.360nMAssay Description:Binding affinity towards Opioid receptor kappa 1 by displacing the radioligand [3H]U-69593 from guinea pig brain membraneMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Displacement of [3H]diprenorphine from human kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Binding affinity for 1 uM [3H]-diprenorphine against human Opioid receptor kappa expressed in chinese hamster ovary cells (CHO cells)More data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Agonistic activity against human k-opioid receptor using [3H]diprenorphineMore data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Displacement of [3H]diprenorphine binding from human kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.70nMAssay Description:Displacement of [3H]diprenorphine from human kappa opioid receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 4.5nMAssay Description:Displacement of [3H]diprenorphine from human KOPR expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 220nMAssay Description:Binding affinity towards Opioid receptor mu 1 by displacing the radioligand [3H]DAMGO from guinea pig brain membraneMore data for this Ligand-Target Pair
Affinity DataKi: 220nMAssay Description:Binding affinity towards Opioid receptor mu 1 in guinea pig brain membranes using [3H]DAMGO as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 2.50E+3nMAssay Description:Binding affinity towards Opioid receptor delta 1 in guinea pig brain membranes using [3H]naltrindole as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 2.50E+3nMAssay Description:Binding affinity towards Opioid receptor delta 1 by displacing the radioligand [3H]naltrindole from guinea pig brain membraneMore data for this Ligand-Target Pair
Affinity DataEC50: 3.40nMAssay Description:Concentration required to enhance [35S]-GTP-gammaS, binding to human Opioid receptor kappa expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 3.40nMAssay Description:Binding potency at human kappa opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 11nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO cell membranes assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataEC50: 6.30nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO cells assessed as increase of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataEC50: 5.70nMAssay Description:Agonist activity at human KOPR expressed in CHO cells assessed as [35S]GTPgammaS binding after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataEC50: 4.5nMAssay Description:Activation of human k-opioid receptor as increased [35S]GTPcS binding More data for this Ligand-Target Pair
Affinity DataEC50: 46nMAssay Description:Inhibitory activity in stimulating [35S]-GTP-gamma S binding mediated by the Opioid receptor kappa 1 in chinese Hamster Ovary (CHO) cell membranes wa...More data for this Ligand-Target Pair