BDBM50151661 CHEMBL3752296

SMILES COc1ccc2CCCN(CCCNC(=O)c3cccc4NC(=O)[C@@H](C)Nc34)c2c1

InChI Key InChIKey=FBGWKDHQIRVFSD-OAHLLOKOSA-N

Data  7 IC50  9 Kd  1 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50151661   

TargetCREB-binding protein(Homo sapiens (Human))
University Of Freiburg

Curated by ChEMBL
LigandPNGBDBM50151661(CHEMBL3752296)
Affinity DataIC50:  323nMAssay Description:Inhibition of CBP (unknown origin) by alphascreen assayMore data for this Ligand-Target Pair
TargetCREB-binding protein(Homo sapiens (Human))
University Of Freiburg

Curated by ChEMBL
LigandPNGBDBM50151661(CHEMBL3752296)
Affinity DataIC50:  580nMAssay Description:Displacement of biotinylated ligand from CBP (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
TargetBromodomain-containing protein 4(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50151661(CHEMBL3752296)
Affinity DataIC50:  1.30E+4nMAssay Description:Displacement of biotinylated ligand from BRD4 bromodomain-1 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCREB-binding protein(Homo sapiens (Human))
University Of Freiburg

Curated by ChEMBL
LigandPNGBDBM50151661(CHEMBL3752296)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Halo-tagged histone H3.3 binding to NanoLuc luciferase conjugated CBP (unknown origin) expressed in HEK293 cells after overnight incuba...More data for this Ligand-Target Pair
TargetCREB-binding protein(Homo sapiens (Human))
University Of Freiburg

Curated by ChEMBL
LigandPNGBDBM50151661(CHEMBL3752296)
Affinity DataIC50:  323nMAssay Description:Inhibition of CBP (unknown origin) by AlphaScreen assayMore data for this Ligand-Target Pair
TargetCREB-binding protein(Homo sapiens (Human))
University Of Freiburg

Curated by ChEMBL
LigandPNGBDBM50151661(CHEMBL3752296)
Affinity DataIC50:  323nMAssay Description:Inhibition of CREBBP (unknown origin) by alpha screen assayMore data for this Ligand-Target Pair
TargetCREB-binding protein(Homo sapiens (Human))
University Of Freiburg

Curated by ChEMBL
LigandPNGBDBM50151661(CHEMBL3752296)
Affinity DataIC50:  316nMAssay Description:Inhibition of human CREBBPMore data for this Ligand-Target Pair