BDBM50151661 CHEMBL3752296

SMILES COc1ccc2CCCN(CCCNC(=O)c3cccc4NC(=O)[C@@H](C)Nc34)c2c1

InChI Key InChIKey=FBGWKDHQIRVFSD-OAHLLOKOSA-N

Data  7 IC50  9 Kd  1 EC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50151661   

TargetCREB-binding protein(Homo sapiens (Human))
University Of Freiburg

Curated by ChEMBL

LigandBDBM50151661(CHEMBL3752296)Copy SMILESCopy InChI

Affinity DataKd:  390nMAssay Description:Inhibition of human His6-tagged CREBBP expressed in competent Escherichia coli BL21 (DE3) cells by isothermal titration calorimetryMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPDBSimilars

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
Copy BDB DOI

TargetBromodomain-containing protein 4(Homo sapiens (Human))
University Of Freiburg

Curated by ChEMBL

LigandBDBM50151661(CHEMBL3752296)Copy SMILESCopy InChI

Affinity DataKd:  1.40E+3nMAssay Description:Inhibition of human BRD4 by isothermal titration calorimetryMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPDBSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI