BDBM35554 thiophene scaffold, 21

SMILES CC(C)N(C(=O)[C@H]1CC[C@H](C)CC1)c1cc(sc1C(O)=O)-c1ccccc1

InChI Key InChIKey=RZXQBIKGWSLVEK-JCNLHEQBSA-N

Data  8 IC50  2 Kd

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 35554   

TargetRNA-directed RNA polymerase(Hepacivirus C)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM35554(thiophene scaffold, 21)
Affinity DataKd:  427nMAssay Description:Inhibition of HCV NS5B polymerase L419M mutantMore data for this Ligand-Target Pair
TargetRNA-directed RNA polymerase(Hepacivirus C)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM35554(thiophene scaffold, 21)
Affinity DataKd:  33nMAssay Description:Inhibition of HCV NS5B polymerase M414T mutantMore data for this Ligand-Target Pair