BDBM10301 CHEMBL64582::Isatin analog 5::methyl 1-methyl-2,3-dioxo-2,3-dihydro-1H-indole-5-carboxylate

SMILES COC(=O)c1ccc2N(C)C(=O)C(=O)c2c1

InChI Key InChIKey=HENVEYFKOOGIOO-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 10301   

TargetGenome polyprotein(Human rhinovirus B)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM10301(CHEMBL64582 | Isatin analog 5 | methyl 1-methyl-2,...)
Affinity DataKi:  3.00E+4nMAssay Description:Inhibition of human rhinovirus 3C proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Glaxosmithkline

LigandPNGBDBM10301(CHEMBL64582 | Isatin analog 5 | methyl 1-methyl-2,...)
Affinity DataIC50:  1.50E+4nMpH: 7.5 T: 2°CAssay Description:The substrate peptides terminating in AMC/AFC are processed by caspases with or without inhibitors, and the accumulation of AMC/AFC was assessed with...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed