BDBM104029 Aryl Nilutamide HDACi analog 14d
SMILES CC1(C)N(Cc2ccc(cc2)-c2cn(CCCCCCC(=O)NO)nn2)C(=O)N(C1=O)c1ccc(C#N)c(c1)C(F)(F)F
InChI Key InChIKey=BJZVXZMNIAKNHY-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 104029
Affinity DataKi: 460nM IC50: 690nMAssay Description:A series of dilutions of the compounds were prepared with 10% DMSO in HDAC assay buffer, and 5uL of the dilution was added to a 50uL reaction so that...More data for this Ligand-Target Pair
Affinity DataIC50: 690nMAssay Description:Inhibition of HDAC (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 690nMAssay Description:Inhibition of AR (unknown origin)More data for this Ligand-Target Pair
TargetAndrogen receptor(Rattus norvegicus (Rat))
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
National Institute Of Pharmaceutical Education And Research (Niper) - Ahmedabad
Curated by ChEMBL
Affinity DataIC50: 690nMAssay Description:Displacement of [3H]-mibolerone from rat androgen receptor incubated for 4 hrs by radioligand binding assayMore data for this Ligand-Target Pair