BDBM105381 US8575203, I-125.23
SMILES Fc1ccc(Cn2cccc(C(=O)NCC#Cc3ccc4nccc(OC[C@@H]5CCCNC5)c4c3)c2=O)cc1F
InChI Key InChIKey=SVQADSMQOQMXGM-HSZRJFAPSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 105381
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 4nMAssay Description:The activity of the compounds according to the invention on the kinase PDK1 which inhibits the signal transduction pathway is determined in an in vit...More data for this Ligand-Target Pair