BDBM10625 ({[bis(propan-2-ylamino)phosphoryl]oxy}(propan-2-ylamino)phosphoryl)(propan-2-yl)amine::CHEMBL494887::iso-OMPA::tetra(monoisopropyl)pyrophosphortetramide

SMILES CC(C)NP(=O)(NC(C)C)OP(=O)(NC(C)C)NC(C)C

InChI Key InChIKey=IOIMDJXKIMCMIG-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 10625   

TargetAcetylcholinesterase(Homo sapiens (Human))
National Institutes of Health

LigandPNGBDBM10625(({[bis(propan-2-ylamino)phosphoryl]oxy}(propan-2-y...)
Affinity DataIC50:  3.40E+5nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
National Institutes of Health

LigandPNGBDBM10625(({[bis(propan-2-ylamino)phosphoryl]oxy}(propan-2-y...)
Affinity DataIC50:  980nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
National Institutes of Health

LigandPNGBDBM10625(({[bis(propan-2-ylamino)phosphoryl]oxy}(propan-2-y...)
Affinity DataIC50:  134nMpH: 8.0Assay Description:The reaction mixture was consisted of 100 µL of the total volume. To the solution of PBS (pH 8.0, 30 µL) consisted of KH2PO4 and K2HPO4 in 96-well pl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Institute For Natural Products Applications And Research Technologies

Curated by ChEMBL
LigandPNGBDBM10625(({[bis(propan-2-ylamino)phosphoryl]oxy}(propan-2-y...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of electric eel AChE incubated for 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Institute For Natural Products Applications And Research Technologies

Curated by ChEMBL
LigandPNGBDBM10625(({[bis(propan-2-ylamino)phosphoryl]oxy}(propan-2-y...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of electric eel AchE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Institute For Natural Products Applications And Research Technologies

Curated by ChEMBL
LigandPNGBDBM10625(({[bis(propan-2-ylamino)phosphoryl]oxy}(propan-2-y...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of electric eel AChE incubated for 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
National Institutes of Health

LigandPNGBDBM10625(({[bis(propan-2-ylamino)phosphoryl]oxy}(propan-2-y...)
Affinity DataIC50:  733nMAssay Description:Inhibition of human plasma BuchE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed