BDBM10873 4-[(2-aminopyrimidin-4-yl)amino]benzene-1-sulfonamide::CHEMBL6633::US9616064, Compound 1aa::aromatic/heteroaromatic sulfonamide 18

SMILES Nc1nccc(Nc2ccc(cc2)S(N)(=O)=O)n1

InChI Key InChIKey=QOAXQANKSMHFKJ-UHFFFAOYSA-N

Data  105 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 10873   

TargetBeta-carbonic anhydrase 1(Mycobacterium tuberculosis)
Kochi Medical School

LigandPNGBDBM10873(4-[(2-aminopyrimidin-4-yl)amino]benzene-1-sulfonam...)
Affinity DataKi:  750nM ΔG°:  -8.21kcal/molepH: 8.3 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed