BDBM110189 1-(2,4-Dihydroxyphenyl)-3-(thiophen-2-yl)propenone (9)
SMILES Oc1ccc(C(=O)\C=C\c2cccs2)c(O)c1
InChI Key InChIKey=HOJWEOLTZCQNJD-GQCTYLIASA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 110189
Affinity DataIC50: 5.62E+4nMpH: 7.5 T: 2°CAssay Description:Inhibition of µ-calpain was assayed in the reaction buffer (50 mM Tris-HCl, 50 mM NaCl, 1 mM EDTA, 1 mM EGTA and 5 mM β-mercaptoethanol, pH...More data for this Ligand-Target Pair
Affinity DataIC50: 5.30E+4nMpH: 5.5 T: 2°CAssay Description:Inhibition of cathepsin L was assayed in reaction buffer (0.1M NaOAc-HCl, 1 mM EDTA, 0.1% β-mercaptoethanol, pH 5.5) containing 20 µM subst...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMpH: 5.5 T: 2°CAssay Description:Inhibition of cathepsin B was assayed in reaction buffer (50 mM NaOAc-HCl, 2 mM dithiothreitol, 2 mM EDTA, pH 5.5) containing 20 µM substrate an...More data for this Ligand-Target Pair
Affinity DataIC50: 3.99E+4nMpH: 7.5 T: 2°CAssay Description:Inhibition of m-calpain was assayed in the reaction buffer (50 mM Tris-HCl, 100 mM NaCl, 5 mM β-mercaptoethanol, and 1 mM EDTA, pH 7.5) with 50 ...More data for this Ligand-Target Pair