BDBM110190 1-(2,4-Dihydroxyphenyl)-3-(furan-2-yl)propenone (10)
SMILES Oc1ccc(C(=O)\C=C\c2ccco2)c(O)c1
InChI Key InChIKey=JGFMSPGSNOQPCH-GQCTYLIASA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 110190
Affinity DataIC50: 8.67E+4nMpH: 7.5 T: 2°CAssay Description:Inhibition of µ-calpain was assayed in the reaction buffer (50 mM Tris-HCl, 50 mM NaCl, 1 mM EDTA, 1 mM EGTA and 5 mM β-mercaptoethanol, pH...More data for this Ligand-Target Pair
Affinity DataIC50: 2.54E+4nMpH: 7.5 T: 2°CAssay Description:Inhibition of m-calpain was assayed in the reaction buffer (50 mM Tris-HCl, 100 mM NaCl, 5 mM β-mercaptoethanol, and 1 mM EDTA, pH 7.5) with 50 ...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Guru Ghasidas Vishwavidyalaya (A Central University)
Curated by ChEMBL
Guru Ghasidas Vishwavidyalaya (A Central University)
Curated by ChEMBL
Affinity DataIC50: 2.49E+3nMAssay Description:Competitive inhibition of PTP1B (unknown origin) using p-nitrophenyl phosphate as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 9.05E+4nMpH: 5.5 T: 2°CAssay Description:Inhibition of cathepsin L was assayed in reaction buffer (0.1M NaOAc-HCl, 1 mM EDTA, 0.1% β-mercaptoethanol, pH 5.5) containing 20 µM subst...More data for this Ligand-Target Pair
Affinity DataIC50: 6.06E+4nMpH: 5.5 T: 2°CAssay Description:Inhibition of cathepsin B was assayed in reaction buffer (50 mM NaOAc-HCl, 2 mM dithiothreitol, 2 mM EDTA, pH 5.5) containing 20 µM substrate an...More data for this Ligand-Target Pair