BDBM110192 3-(2,4-Dihydroxyphenyl)-1-(furan-2-yl)propenone (14)
SMILES Oc1ccc(\C=C\C(=O)c2ccco2)c(O)c1
InChI Key InChIKey=RSFHWDSEGUCJOP-GQCTYLIASA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 110192
Affinity DataIC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:Inhibition of µ-calpain was assayed in the reaction buffer (50 mM Tris-HCl, 50 mM NaCl, 1 mM EDTA, 1 mM EGTA and 5 mM β-mercaptoethanol, pH...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:Inhibition of m-calpain was assayed in the reaction buffer (50 mM Tris-HCl, 100 mM NaCl, 5 mM β-mercaptoethanol, and 1 mM EDTA, pH 7.5) with 50 ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.280nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate assessed as monophenolase activityMore data for this Ligand-Target Pair
Affinity DataIC50: 2.87E+3nMpH: 5.5 T: 2°CAssay Description:Inhibition of cathepsin L was assayed in reaction buffer (0.1M NaOAc-HCl, 1 mM EDTA, 0.1% β-mercaptoethanol, pH 5.5) containing 20 µM subst...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0433nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate assessed as diphenolase activityMore data for this Ligand-Target Pair
Affinity DataIC50: 4.95E+4nMpH: 5.5 T: 2°CAssay Description:Inhibition of cathepsin B was assayed in reaction buffer (50 mM NaOAc-HCl, 2 mM dithiothreitol, 2 mM EDTA, pH 5.5) containing 20 µM substrate an...More data for this Ligand-Target Pair