BDBM115384 US8637500, 205
SMILES Cn1cnc2ccc(cc12)-c1nccnc1Oc1ccc(Nc2ccccn2)cc1
InChI Key InChIKey=XBUSHSPBQAPHCW-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 115384
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Rattus norvegicus (rat))
Amgen
US Patent
Amgen
US Patent
Affinity DataIC50: 3.90nMT: 2°CAssay Description:An IMAP TR-FRET assay was used to analyze the enzyme activity (Molecular Devices Corp., Sunnyvale Calif.). 5 μL of serial diluted PDE10A (BPS Bi...More data for this Ligand-Target Pair