BDBM11578 5-(aminomethyl)-6-(2,4-dichlorophenyl)-2-phenylpyrimidin-4-amine::Aminomethylpyrimidine 1c::CHEMBL36020

SMILES NCc1c(N)nc(nc1-c1ccc(Cl)cc1Cl)-c1ccccc1

InChI Key InChIKey=CTFXGZSHNLIYDI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 11578   

TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Hoffmann-La Roche

LigandPNGBDBM11578(5-(aminomethyl)-6-(2,4-dichlorophenyl)-2-phenylpyr...)
Affinity DataIC50:  10nMAssay Description:DPP-IV inhibitors were measured for their ability to inhibit DPP-IV mediated cleavage of Ala-Pro-7-amido-4-trifluoromethylcoumarin in a fluorogenic a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Hoffmann-La Roche

LigandPNGBDBM11578(5-(aminomethyl)-6-(2,4-dichlorophenyl)-2-phenylpyr...)
Affinity DataIC50:  10nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM11578(5-(aminomethyl)-6-(2,4-dichlorophenyl)-2-phenylpyr...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human liver microsome Cytochrome P3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed