BDBM1164 (3R,4S,5S,6R)-2,7-Dibenzyl-3,6-bis(2-phenylethyl)-4,5-dihydroxy-1,2,7-thiadiazepan 1,1-Dioxide::(3R,4S,5S,6R)-2,7-dibenzyl-4,5-dihydroxy-3,6-bis(2-phenylethyl)-1,2,7-thiadiazepane-1,1-dione::Cyclic Sulfamide 5

SMILES O[C@@H]1[C@@H](O)[C@@H](CCc2ccccc2)N(Cc2ccccc2)S(=O)(=O)N(Cc2ccccc2)[C@@H]1CCc1ccccc1

InChI Key InChIKey=DHQTXGHHAQJESR-WZJLIZBTSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 1164   

TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Uppsala University

LigandPNGBDBM1164((3R,4S,5S,6R)-2,7-Dibenzyl-3,6-bis(2-phenylethyl)-...)
Affinity DataKi:  14.7nM ΔG°:  -11.1kcal/mole IC50:  200nMpH: 5.5 T: 2°CAssay Description:The IC50 value is the inhibitor concentration that results in 50% of HIV-1 protease activity measured by a spectrophotometric assay using a chromopho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed