BDBM117736 US8653087, III-416

SMILES CN1CCC(CN2CCN(CC2)c2ncc3ncnc(Nc4cc(ccc4C)C(=O)Nc4cccc(c4)C(C)(C)C)c3n2)CC1

InChI Key InChIKey=BEJBLIGQDMLAOM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 117736   

TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM117736(US8653087, III-416)
Affinity DataIC50:  1nMpH: 7.5Assay Description:The final concentration of DMSO is 5%. 10 μL of the B-Raf (V600E)-kinase solution are pipetted in (containing 0.5 ng B-Raf (V600E)-kinase in 20 ...More data for this Ligand-Target Pair
In DepthDetails US Patent