BDBM119558 US8680275, 114

SMILES Cc1cncc(n1)N1C[C@@H]2CCN(C[C@H]12)C(=O)c1ccc(F)cc1-n1nccn1

InChI Key InChIKey=MQUOGPOCGAQVDA-KSSFIOAISA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 119558   

TargetOrexin receptor type 2(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM119558(US8680275, 114)
Affinity DataKi:  494nM ΔG°:  -7.99kcal/moleT: 2°CAssay Description:HEK293 stably expressing human orexin-2 receptor (Genebank accession number NM 001526) were grown to confluency in DMEM/F12 (Gibco, Cat #11039), in D...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM119558(US8680275, 114)
Affinity DataKi:  1.00E+4nM ΔG°:  -6.34kcal/moleT: 2°CAssay Description:Chinese ovary cells (CHO) stably expressing human orexin 1 receptor (Genebank accession number NM 001526) were grown to confluency in DMEM/F12 (Gibco...More data for this Ligand-Target Pair
In DepthDetails US Patent