BDBM11985 4-(2,5-dimethyl-1H-pyrrol-1-yl)-2-hydroxybenzoic acid::Salicylic acid derivative, compound 1::chemical diversity library compound 10
SMILES Cc1ccc(C)n1-c1ccc(C(O)=O)c(O)c1
InChI Key InChIKey=WAYCNXGAKFXIKA-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 11985
Affinity DataKi: 1.50E+3nM ΔG°: -7.99kcal/mole IC50: 3.80E+3nMpH: 7.2 T: 2°CAssay Description:For selected lead compounds from fluorescence-based high-throughput screening, Km and Vmax were calculated using the double-reciprocal Lineweaver-Bur...More data for this Ligand-Target Pair
TargetDual specificity protein phosphatase 3(Homo sapiens (Human))
Institute For Medical Research
Curated by ChEMBL
Institute For Medical Research
Curated by ChEMBL
Affinity DataKi: 1.28E+4nMAssay Description:Inhibition of recombinant vaccina H1-related phosphatase expressed in Escherichia coli by Michaelis-Menton kinetic studiesMore data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of Staphylococcus aureus Smith DNA helicase DnaC assessed as strand unwinding after 30 mins by FRET assayMore data for this Ligand-Target Pair
TargetEphrin type-A receptor 4 [1-949,A922V](Homo sapiens (Human))
Sanford-Burnham Medical Research Institute
Sanford-Burnham Medical Research Institute
Affinity DataIC50: 1.30E+3nMpH: 7.5Assay Description:Protein A-coasted wells (from Pierce Biotechnology) were used to immobilize Eph receptor Fc fusion proteins (from R&D systems)incubated at 1 ug/ml in...More data for this Ligand-Target Pair