BDBM120079 CHEMBL257153::US8697716, 35

SMILES O=C(Nc1ccc(cc1C1=CCS(=O)(=O)CC1)C1CCNCC1)c1ncc([nH]1)C#N

InChI Key InChIKey=IRZATOLKYBKBAO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 120079   

TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM120079(CHEMBL257153 | US8697716, 35)
Affinity DataIC50:  60nMAssay Description:Inhibition of FMSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM120079(CHEMBL257153 | US8697716, 35)
Affinity DataIC50:  73nMAssay Description:The compounds of the present invention are also specific inhibitors of c-Kit. Selection of preferred compounds of Formula I for use as c-Kit inhibito...More data for this Ligand-Target Pair
In DepthDetails US Patent