BDBM120391 US8703771, 4

SMILES CCN1CCN(CC1)C1CCc2cc(ccc12)C(=O)Nc1ccc(C)c(Nc2nccc(n2)-c2cccnc2)c1

InChI Key InChIKey=JVGNHFZOVWJKER-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 120391   

TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Harbin Gloria Pharmaceuticals

US Patent
LigandPNGBDBM120391(US8703771, 4)
Affinity DataIC50:  6.30nMpH: 7.5 T: 2°CAssay Description:The activity of the compounds of this invention on Abl, c-Kit and PDGFR kinases was tested by Mobility Shift Assay (MSA). Kinase buffer: 62.5 mM HEPE...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Harbin Gloria Pharmaceuticals

US Patent
LigandPNGBDBM120391(US8703771, 4)
Affinity DataIC50:  15nMpH: 7.5 T: 2°CAssay Description:The activity of the compounds of this invention on Abl, c-Kit and PDGFR kinases was tested by Mobility Shift Assay (MSA). Kinase buffer: 62.5 mM HEPE...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Harbin Gloria Pharmaceuticals

US Patent
LigandPNGBDBM120391(US8703771, 4)
Affinity DataIC50:  26nMpH: 7.5 T: 2°CAssay Description:The activity of the compounds of this invention on Abl, c-Kit and PDGFR kinases was tested by Mobility Shift Assay (MSA). Kinase buffer: 62.5 mM HEPE...More data for this Ligand-Target Pair
In DepthDetails US Patent