BDBM120392 US8703771, 5
SMILES CC(C)N1CCN(CC1)C1CCc2cc(ccc12)C(=O)Nc1ccc(C)c(Nc2nccc(n2)-c2cccnc2)c1
InChI Key InChIKey=PZINVJUNZRLUIM-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 120392
Affinity DataIC50: 5.40nMpH: 7.5 T: 2°CAssay Description:The activity of the compounds of this invention on Abl, c-Kit and PDGFR kinases was tested by Mobility Shift Assay (MSA). Kinase buffer: 62.5 mM HEPE...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Harbin Gloria Pharmaceuticals
US Patent
Harbin Gloria Pharmaceuticals
US Patent
Affinity DataIC50: 18nMpH: 7.5 T: 2°CAssay Description:The activity of the compounds of this invention on Abl, c-Kit and PDGFR kinases was tested by Mobility Shift Assay (MSA). Kinase buffer: 62.5 mM HEPE...More data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Harbin Gloria Pharmaceuticals
US Patent
Harbin Gloria Pharmaceuticals
US Patent
Affinity DataIC50: 23nMpH: 7.5 T: 2°CAssay Description:The activity of the compounds of this invention on Abl, c-Kit and PDGFR kinases was tested by Mobility Shift Assay (MSA). Kinase buffer: 62.5 mM HEPE...More data for this Ligand-Target Pair