BDBM12255 AZD0530::CHEMBL217092::Compound 33::N-(5-chloro-2H-1,3-benzodioxol-4-yl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]-5-(oxan-4-yloxy)quinazolin-4-amine::Saracatinib::med.21724, Compound 189

SMILES CN1CCN(CCOc2cc(OC3CCOCC3)c3c(Nc4c5OCOc5ccc4Cl)ncnc3c2)CC1

InChI Key InChIKey=OUKYUETWWIPKQR-UHFFFAOYSA-N

Data  2 KI  28 IC50  2 Kd  1 EC50

PDB links: 5 PDB IDs match this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 12255   

TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL

LigandBDBM12255(AZD0530 | CHEMBL217092 | Compound 33 | N-(5-chloro...)Copy SMILESCopy InChI

Affinity DataIC50:  2.70nMAssay Description:Inhibition of c-SRCMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLMCE
MMDBPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
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