BDBM123365 US8742106, 5.5

SMILES COc1nc(cs1)-c1nn(C)c2nc(OCC(=O)N[C@@H](C)c3ccc(C)cc3)cc(C)c12

InChI Key InChIKey=JBVHBPMXFJEBSE-HNNXBMFYSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 123365   

TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM123365(US8742106, 5.5)
Affinity DataKd:  15nMpH: 7.5 T: 2°CAssay Description:For crude cell membrane preparations, cells (CHO, Chinese hamster ovary or HEK, human embryonic kidney) expressing human orexin 1 or human orexin 2 r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM123365(US8742106, 5.5)
Affinity DataKd:  37nMpH: 7.5 T: 2°CAssay Description:For crude cell membrane preparations, cells (CHO, Chinese hamster ovary or HEK, human embryonic kidney) expressing human orexin 1 or human orexin 2 r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent