BDBM125927 6-Chloro-9-(prop-2-yn-1-yl)-9H-purin-2-amine (2)

SMILES Nc1nc(Cl)c2ncn(CC#C)c2n1

InChI Key InChIKey=BIYFIQUJKQFEMK-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 125927   

TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
East China University of Science and Technology

LigandPNGBDBM125927(6-Chloro-9-(prop-2-yn-1-yl)-9H-purin-2-amine (2))
Affinity DataIC50:  2.32E+5nMpH: 6.5Assay Description:Enzymatic activity of enzyme was evaluated using pNPP assay. Briefly, a reaction mixture (100 無) containing 50 mM MOPS (pH 6.5), 2 mM pNPP and recom...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
East China University of Science and Technology

LigandPNGBDBM125927(6-Chloro-9-(prop-2-yn-1-yl)-9H-purin-2-amine (2))
Affinity DataIC50: >8.00E+4nMpH: 6.5Assay Description:Enzymatic activity of enzyme was evaluated using pNPP assay. Briefly, a reaction mixture (100 無) containing 50 mM MOPS (pH 6.5), 2 mM pNPP and recom...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University of Science and Technology

LigandPNGBDBM125927(6-Chloro-9-(prop-2-yn-1-yl)-9H-purin-2-amine (2))
Affinity DataIC50: >8.00E+4nMpH: 6.5Assay Description:Enzymatic activity of enzyme was evaluated using pNPP assay. Briefly, a reaction mixture (100 無) containing 50 mM MOPS (pH 6.5), 2 mM pNPP and recom...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 6(Homo sapiens (Human))
East China University of Science and Technology

LigandPNGBDBM125927(6-Chloro-9-(prop-2-yn-1-yl)-9H-purin-2-amine (2))
Affinity DataIC50: >8.00E+4nMpH: 6.5Assay Description:Enzymatic activity of enzyme was evaluated using pNPP assay. Briefly, a reaction mixture (100 無) containing 50 mM MOPS (pH 6.5), 2 mM pNPP and recom...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
East China University of Science and Technology

LigandPNGBDBM125927(6-Chloro-9-(prop-2-yn-1-yl)-9H-purin-2-amine (2))
Affinity DataIC50: >8.00E+4nMpH: 6.5Assay Description:Enzymatic activity of enzyme was evaluated using pNPP assay. Briefly, a reaction mixture (100 無) containing 50 mM MOPS (pH 6.5), 2 mM pNPP and recom...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed