BDBM1266 L-682, 679 analog 25::tert-butyl N-[(2S,3S,5R)-5-benzyl-5-{[(1S,2S)-1-{[(1S)-1-carbamoyl-2-phenylethyl]carbamoyl}-2-methylbutyl]carbamoyl}-3-hydroxy-1-phenylpentan-2-yl]carbamate
SMILES CCC(C)[C@H](NC(=O)[C@@H](C[C@H](O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C)Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
InChI Key InChIKey=BPOHHXKBFDNMAK-JZDOKRBOSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 1266
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Sharp and Dohme Research Laboratories
Merck Sharp and Dohme Research Laboratories
Affinity DataIC50: 0.25nMpH: 5.5 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair